声触诊组织定量技术鉴别诊断甲状腺良恶性结节

发布时间：2018-03-03 17:40

本文选题：声触诊组织定量　切入点：甲状腺结节　出处：《中国医学影像技术》2015年03期 　论文类型：期刊论文

【摘要】：目的探讨声触诊组织定量成像(VTQ)鉴别诊断甲状腺良恶性结节的价值。方法收集48例经手术或穿刺病理证实的甲状腺结节患者,均行常规超声及VTQ检查,获得结节及结节周围组织的剪切波速度(SWV),采用ROC曲线进行统计学分析。结果良性结节及其周围组织的SWV分别为(2.05±0.25)m/s[95%可信区间(CI):1.95~2.15m/s]、(1.78±0.26)m/s(95%CI:1.68~1.88 m/s),恶性结节及其周围组织SWV分别为(3.57±1.29)m/s(95%CI:3.06~4.09m/s)、(1.85±0.29)m/s(95%CI:1.73~1.96m/s)。良性结节与恶性结节、良性结节与其周围组织、恶性结节与其周围组织间SWV的差异均有统计学意义(P均0.001),而良性结节周围组织与恶性结节周围组织间SWV的差异无统计学意义(P=0.5006)。应用SWV诊断甲状腺恶性结节的ROC曲线下面积为0.9927,截断值为2.416m/s,敏感度、特异度、阳性预测值、阴性预测值、阳性似然比及阴性似然比分别为88.89%(24/27)、96.43%(27/28)、96.00%(24/25)、90.00%(27/30)、24.89及0.12。结论 VTQ检查能够通过SWV值反映出结节及其周围组织的硬度,在对甲状腺结节良恶性的鉴别诊断中具有重要价值。
[Abstract]:Objective to investigate the value of acoustic palpation tissue quantitative imaging (VTQQ) in differential diagnosis of benign and malignant thyroid nodules. Methods 48 patients with thyroid nodules confirmed by operation or puncture pathology were examined by conventional ultrasound and VTQ. The shear wave velocities of nodules and surrounding tissues were obtained and analyzed statistically by ROC curve. Results the SWV of benign nodules and their surrounding tissues were 2.05 卤0.25 m / s [95% CI: 1.952.15mr / s] 1.78 卤0.26m / s 95% CI: 1.681.88 m / s, and the SWV of malignant nodules and their surrounding tissues were 3.57 卤1.29mprs95CI3.064.09ms/ / r = 1.85 卤0.29ms-1 / 95 respectively. Benign and malignant nodules, Benign nodules and their surrounding tissues, There were significant differences in SWV between malignant nodules and their surrounding tissues (P < 0.001), but there was no significant difference in SWV between benign and malignant nodules. SWV was used to diagnose the ROC curvature of malignant thyroid nodules. The area below the line is 0.9927, the truncation is 2.416m / s, the sensitivity is, The specificity, the positive predictive value, the negative predictive value, the positive likelihood ratio and the negative likelihood ratio were 88.89 and 96.43, respectively. Conclusion VTQ can reflect the hardness of the nodules and their surrounding tissues by SWV. It has important value in the differential diagnosis of benign and malignant thyroid nodules.
【作者单位】：暨南大学第二临床医学院;深圳市人民医院超声科;
【分类号】：R445.1;R736.1

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