孤立性肺小结节CT表现与病理对照分析

发布时间：2018-03-04 15:17

本文选题：孤立性肺小结节　切入点：肺癌　出处：《宁夏医科大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:分析不同病理类型的孤立性肺小结节(SPN)的胸部CT表现(大小、生长部位及形态学特征),探讨其对SPN定性诊断的价值。方法:回顾性分析经病理证实的94例SPN患者行多层螺旋CT扫描后处理的图像,观察结节大小、分布、边缘及内部征象并与病理结果对照。结果:94例SPN中,良性结节26例(占27.7%),其中包括炎性结节13例(13.8%),结核瘤5例(5.3%),错构瘤7例(7.4%),硬化性血管瘤1例(1.1%)。恶性结节68例(占72.3%),其中包括腺癌51例(54.3%),鳞癌11例(11.7%),腺鳞癌1例(1.1%),小细胞癌2例(2.1%),大细胞癌1例(1.1%),类癌2例(2.1%)。良性结节平均直径(1.87±0.60)cm,恶性结节平均直径(2.09±0.67)cm。所有病例中左肺结节共46例,其中恶性33例,良性13例;右肺结节48例,其中恶性35例,良性13例。恶性结节在肺叶的分布总体差异无统计学意义(P0.05)。结节的分叶征、毛刺征、胸膜凹陷征、血管集束征的发生率在恶性组明显高于良性组,差异有统计学意义(P0.05)。结论:对SPN患者早期行CT检查,分析其边缘及内部形态特征,可作出对SPN的良恶性鉴别诊断,对临床治疗具有重要的指导价值。
[Abstract]:Objective: to analyze the chest CT findings (size) of solitary pulmonary nodules (SPNs) with different pathological types. To explore the value of growth site and morphological features in the qualitative diagnosis of SPN methods: the image of 94 cases of SPN confirmed by pathology were analyzed retrospectively and the size and distribution of the nodules were observed. The marginal and internal signs were compared with pathological findings. Results in 94 cases of SPN, There were 26 benign nodules (27.7%), including 13 cases of inflammatory nodules, 5 cases of tuberculoma, 7 cases of hamartoma, 1 case of sclerosing hemangioma, 1 case of sclerosing hemangioma, 68 cases of malignant nodules, including 51 cases of adenocarcinoma, 11 cases of squamous cell carcinoma, 11 cases of squamous cell carcinoma and 1 case of adenosquamous carcinoma. The mean diameters of benign and malignant nodules were 1.87 卤0.60 cm and 2.09 卤0.67 cm respectively. There were 46 cases of left pulmonary nodules in all cases. Among them, 33 cases were malignant, 13 cases were benign, 48 cases were right pulmonary nodule, of which 35 cases were malignant, 13 cases were benign. There was no significant difference in the distribution of malignant nodules in pulmonary lobes (P 0.05). The incidence of vascular cluster sign in malignant group was significantly higher than that in benign group, and the difference was statistically significant (P 0.05). Conclusion: early CT examination and analysis of the edge and internal morphological features of SPN patients can make differential diagnosis of benign and malignant SPN. It has important guiding value for clinical treatment.
【学位授予单位】：宁夏医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R563;R734.2;R730.44

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