放射治疗在寡转移治疗中的研究进展

发布时间：2018-03-04 22:04

本文选题：肿瘤　切入点：寡转移　出处：《肿瘤》2017年05期 　论文类型：期刊论文

【摘要】：肿瘤的转移是一种从局部病变到全身病变的演变过程,其中存在很多中间状态。寡转移属于肿瘤转移过程中的一种状态,是肿瘤生物侵袭过程中较温和的一个阶段。寡转移时转移灶数量有限,是一个介于局部原发灶和广泛远处转移之间的过渡阶段,但该阶段不具备向全身播散的倾向。寡转移的治疗主要以局部治疗为主。随着放疗技术与影像学技术的发展,放射治疗逐步成为一种重要的治疗手段;尤其是立体定向放射治疗技术已被证明是一种安全有效、不良反应小、能有效提高寡转移患者局部控制率及生存期的方法。尽管已取得良好的治疗效果,但立体定向放射治疗在对寡转移的控制中仍面临着各种挑战,尤其在患者的选择标准与治疗策略上。因此,本文就肿瘤寡转移以及放射治疗在寡转移治疗中的临床研究现状及进展进行综述,以期为寡转移患者提供一种更好的治疗方法。
[Abstract]:Tumor metastasis is a process from local lesions to systemic lesions, in which there are many intermediate states. Oligometastasis is a state in the process of tumor metastasis. It is a mild stage in the process of tumor biological invasion. The number of metastatic foci is limited, and it is a transitional stage between local primary tumor and extensive distant metastasis. But this stage does not have the tendency to spread to the whole body. The treatment of oligometastasis is mainly local treatment. With the development of radiotherapy and imaging technology, radiotherapy has gradually become an important treatment method. In particular, stereotactic radiotherapy has been proved to be a safe and effective method with minimal adverse reactions, which can effectively improve the local control rate and survival time of patients with oligometastases. However, stereotactic radiotherapy still faces a variety of challenges in the control of oligometastasis, especially in the selection criteria and treatment strategies of patients. This article reviews the current situation and progress of clinical studies on tumor oligometastasis and radiotherapy in order to provide a better treatment for patients with oligometastasis.
【作者单位】：蚌埠医学院第一附属医院放疗科;
【基金】：安徽省卫生厅“十二五”临床重点专科建设基金资助项目(编号:01Z33)~~
【分类号】：R730.55

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