自动测量方法测定Tei指数在评估法洛四联症胎儿心功能的应用研究

发布时间：2018-03-05 22:05

本文选题：Tei指数　切入点：超声心动图　出处：《新疆医科大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:探讨自动法和手动测量法获取Tei指数(Tei index,TI)在评估法洛四联症(Tetralogy of fallot,TOF)胎儿心功能中的应用价值。方法:收集经胎儿超声心动图诊断为TOF胎儿30例(病例组)和正常胎儿88例(对照组)。利用脉冲多普勒同时获得左室流入道与流出道频谱,分别采用左心室Tei指数(LV-TI)自动测量法和分步手动测量法测量,分析孕龄对测值结果的影响,比较两种方法获得的LV-TI的差异性及两组组间胎儿LV-TI的变化趋势。结果:运用TI自动测量方法获得对照组胎儿LV-TI:0.459±0.051,病例组:0.577±0.038,手动测量法获得对照组胎儿LV-TI:0.444±0.059,病例组:0.579±0.059;结果显示:TI自动测量法获得病例组胎儿LV-TI高于对照组(0.572±0.041对0.459±0.051),两组测值不同差异有统计学意义(t=-10.97,P0.05),两种方法获得对照组胎儿LV-TI测量结果及不同孕龄之间比较差异无统计学意义(P0.05)。不同TOF病理分型重度肺动脉狭窄重型TOF胎儿LV-TI明显大于轻度肺动脉狭窄测量结果(0.625±0.018对0.557±0.030)。结论:TI不受孕龄、心室几何形态影响是较为理想评价TOF胎儿心脏功能的敏感指标,且TI自动测量方法较传统手动测量法更简单、快捷,具有更好的可靠性和重复性,易于在实际及科研工作中推广应用。
[Abstract]:Objective: to evaluate the value of automatic method and manual measurement method in evaluating fetal cardiac function of Tetralogy of fallottoF patients with tetralogy of Fallot. Methods: 30 cases of fetal TOF diagnosed by fetal echocardiography (case group) were collected. And 88 normal fetuses (control group). The left ventricular inflow and outflow tract spectra were simultaneously obtained by pulsed Doppler. The left ventricular Tei index (LV-TI) automatic measurement method and step by step manual measurement method were used to analyze the influence of gestational age on the measured results. Results: the fetal LV-TI:0.459 卤0.051 in the control group, 0. 577 卤0. 038 in the case group, LV-TI:0.444 卤0. 059 in the control group and 0. 579 卤0. 059 in the case group were obtained by using the TI automatic measurement method. The fetal LV-TI in the case group was higher than that in the control group (0.572 卤0.041 vs 0.459 卤0.051), and the difference between the two groups was statistically significant (P 0.05). There was no statistical difference between the two methods in obtaining the fetal LV-TI of the control group and the difference between different gestational ages. Different TOF pathological classification: fetal LV-TI of severe TOF with severe pulmonary stenosis was significantly higher than that of mild pulmonary stenosis (0.625 卤0.018 vs 0.557 卤0.030). Conclusion the fetal LV-TI of severe TOF patients with severe pulmonary stenosis is not affected by gestational age. The influence of ventricular geometry is a sensitive index for evaluating fetal cardiac function in TOF, and TI automatic measurement method is simpler, faster, more reliable and repeatable than traditional manual measurement method. It is easy to be popularized and applied in practice and scientific research.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R714.5;R540.45

【相似文献】