二维与实时三维超声心动图对法乐氏四联症患儿右室收缩功能评价指标的相关性研究

发布时间：2018-03-06 03:32

本文选题：二维超声心动图　切入点：实时三维超声心动图　出处：《中国超声医学杂志》2015年06期 　论文类型：期刊论文

【摘要】：目的探讨二维(2DE)与实时三维超声心动图(RT-3DE)评价法乐氏四联症(TOF)患儿右室收缩功能指标的相关性。方法选择45例TOF患儿及46例正常同龄对照组作为研究对象,获取二维右室收缩功能指标:三尖瓣环侧壁收缩期位移距离(TAPSE),三尖瓣环侧壁收缩期峰值运动速度(TRV),右室心尖四腔观面积收缩率(RVa);应用RT-3DE于心尖偏胸骨旁四腔心采集右室全容积声像图,使用TomTec RV-Function软件分析右室射血分数(RVEF);对TOF组与正常对照组2DE及RT-3DE右室收缩功能指标进行比较并进行相关性分析。结果 TOF组RT-3DE获得的RVEF与2DE各右室收缩功能指标均小于正常对照组(P0.05)。2DE各指标与RT-3DE获得的RVEF均呈正相关性(P0.01),其中TAPSE与RVEF的相关性最好,r=0.574,P=0.000,ROC曲线分析表明TAPSE1.68cm时,评价RVEF45%的灵敏度为80%,特异度为78%(P=0.000)。结论 TOF患儿右室收缩功能减低,RT-3DE使快速无创评估右室射血分数成为可能。
[Abstract]:Objective to investigate the correlation between two-dimensional deoxyribonucleic acid (2DE) and real-time three-dimensional echocardiography (RT-3DEE) in evaluating the right ventricular systolic function in children with tetralogy of Fallot. Methods 45 children with TOF and 46 normal controls were selected as subjects. Obtain two dimensional right ventricular systolic function index: tricuspid annulus lateral wall displacement distance (TAPSEN), tricuspid annulus lateral wall systolic peak velocity (TRV), right ventricular apical four chamber area constriction rate (RVaA). Application of RT-3DE in quadrilateral apical apical cavity cardiac sampling. Set right ventricular full volume sonogram, The right ventricular ejection fraction (RVEFV) was analyzed by TomTec RV-Function software, the right ventricular systolic function indexes of 2DE and RT-3DE in TOF group and normal control group were compared and the correlation analysis was carried out. Results the RVEF and 2DE indexes of right ventricular systolic function obtained by RT-3DE in TOF group were all different. Compared with the normal control group, there was a positive correlation between the RVEF obtained from RT-3DE and P0.05DE, and the correlation between TAPSE and RVEF was the best. The analysis of ROC curve showed that when TAPSE1.68cm was obtained, the correlation between TAPSE and RVEF was the best. The sensitivity of RVEF 45% was 80 and the specificity was 780.0000.Conclusion right ventricular systolic dysfunction and RT-3DE in children with TOF make it possible to evaluate RV ejection fraction quickly and noninvasively.
【作者单位】：武汉市儿童医院超声科;华中科技大学同济医学院附属协和医院超声科;
【分类号】：R540.45;R725.4

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