IDEAL-IQ与MRS定量测量肝脏脂肪含量的可行性及相关性

发布时间：2018-03-06 23:38

本文选题：非酒精性脂肪肝　切入点：肝脏脂肪含量　出处：《放射学实践》2017年05期 　论文类型：期刊论文

【摘要】：目的:探讨非对称回波的最小二程估算法迭代水脂分离技术(IDEAL-IQ)与磁共振波谱(MRS)定量测量肝脏脂肪含量的可行性及相关性。方法:采用IDEAL-IQ和MRS定量测量87例非酒精性脂肪肝患者及20例健康志愿者的肝脏脂肪含量,对比分析IDEAL-IQ、MRS测量的脂肪含量的差异及相关性。结果:107例受检者中IDEAL-IQ扫描成功102例(95.8%,102/107),MRS扫描成功76例(71.0%,76/107),两种检查方法的扫描成功率差异有统计学意义(P0.05)。76例受检者MRS、IDEAL-IQ均扫描成功,此76位受检者由MRS、IDEAL-IQ测得的相对脂质含量(RLC)、脂肪分数(FF)分别为(17.33±10.86)%、(16.28±10.27)%,两者差异无统计学意义(P=0.192)。IDEAL-IQ与MRS测量肝脏脂肪含量相关性的散点图显示两者呈线性关系,Pearson相关性分析显示RLC和FF呈正相关(r=0.784,P=2.613)。结论:MRS、IDEAL-IQ均可定量测量脂肪肝的脂肪含量,两者测量的肝脏脂肪含量呈线性正相关。
[Abstract]:Objective: to investigate the feasibility and correlation of quantitative measurement of liver fat content by iterative water-lipid separation technique (IDEAL-IQ) and magnetic resonance spectroscopy (MRS) using least square estimation method of asymmetric echo. Methods: 87 cases of non-alcohol were quantitatively measured by IDEAL-IQ and MRS. Liver fat content in patients with fatty liver and 20 healthy volunteers. Results among the 107 subjects examined by IDEAL-IQ, 102 cases were successfully scanned by IDEAL-IQ and 76 cases were successfully scanned by Mrs. 76 cases were successfully scanned. The difference of the success rate of the two methods was statistically significant (P0.05 .76 cases), and the success rate of MRSIDEAL-IQ in 76 cases was significantly higher than that in the control group (P < 0.05), and there was a significant difference between the two methods in the success rate of MRSIDEAL-IQ scan, and the difference between the two methods was statistically significant (P < 0.05), and the difference between the two methods was statistically significant (P < 0.05), and the difference between the two methods was statistically significant. The relative lipid contents and FFFs measured by MRS- IDEAL-IQ were 17.33 卤10.86 and 16.28 卤10.27, respectively. There was no significant difference between them. The scattered plot of correlation between them and MRS showed a linear relationship. Pearson correlation analysis showed that there was a linear relationship between them. The results showed that there was a positive correlation between RLC and FF. Conclusion the fat content of fatty liver can be measured quantitatively by the weight MRSI IDEAL-IQ. There was a positive linear correlation between the liver fat content measured by the two methods.
【作者单位】：郑州大学第一附属医院;
【分类号】：R445.2;R575.5

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