多b值DWI鉴别高级别胶质瘤及脑转移瘤

发布时间：2018-03-08 07:28

本文选题：脑转移瘤　切入点：高级别胶质瘤　出处：《临床放射学杂志》2015年10期 　论文类型：期刊论文

【摘要】：目的探讨多b值扩散加权成像(DWI)对高级别胶质瘤和脑转移瘤的鉴别价值。方法对13例高级别胶质瘤和17例脑转移瘤患者进行常规MR及多b值DWI检查,测量肿瘤实质区及瘤周水肿区的D值及D*值,比较肿瘤实质区与瘤周水肿区之间D值及D*值的差异及两种肿瘤之间的差异,并采用t检验。结果脑转移瘤的肿瘤实质区与瘤周水肿区的D值分别为0.94±0.27和1.28±0.40(t=-2.93,P=0.006);D*值分别为5.85±1.57和4.24±1.27(t=3.28,P=0.002)。高级别胶质瘤的肿瘤实质区与瘤周水肿区的D值分别为0.85±0.21和1.20±0.37(t=-2.97,P=0.027);D*值分别为7.44±2.04和4.59±1.22(t=4.316,P=0.004)。脑转移瘤肿瘤实质区的D*平均值为5.85×10-3mm2/s,而高级别胶质瘤肿瘤实质区D*平均值为7.44×10-3mm2/s,两者间差异显著(t=-2.412,P=0.023)。肿瘤实质区的D值、瘤周水肿区D及D*值在两种肿瘤间差异均无统计学意义(P0.05)。结论多b值DWI可以成为脑转移瘤与高级别胶质瘤无创性的鉴别方法。
[Abstract]:Objective to investigate the value of multi-b value diffusion weighted imaging (DWI) in differentiating high grade gliomas from brain metastases. Methods 13 cases of high grade gliomas and 17 cases of brain metastases were examined by conventional Mr and multi b value DWI. The D value and D * value of tumor parenchyma and peritumoral edema were measured, and the difference of D value and D * between tumor parenchyma and peritumoral edema were compared. Results the D values of parenchyma and peritumoral edema of brain metastases were 0.94 卤0.27 and 1.28 卤0.40 ~ 0.40 t ~ (-1) ~ (-2.93N) ~ (0.006) D *, respectively, 5.85 卤1.57 and 4.24 卤1.27 ~ (1.27) ~ (3.28) P _ (0.002) respectively. The D values of parenchyma and peritumoral edema of high-grade gliomas were 0.85 卤0.21 and 1.20 卤0.37 ~ (t) ~ 0.027D*, respectively. The average D * of the parenchymal region of brain metastases was 5.85 脳 10 ~ (-3) mm ~ (-2) / s, while the mean value of D * of the high-grade glioma was 7.44 脳 10 ~ (-3) mm ~ (2) / s. The difference was significant between the two groups. There was no significant difference in D and D * values between the two types of tumors. Conclusion Multi-b DWI may be a noninvasive method for differentiating brain metastases from high grade gliomas.
【作者单位】：安徽医科大学第一附属医院放射科;厦门市儿童医院放射科;
【分类号】：R739.41;R445.2

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