超声在诊断原发性肾小球疾病中的临床应用

发布时间：2018-03-08 17:13

本文选题：超声特征　切入点：原发性肾小球疾病　出处：《青海大学》2014年硕士论文　论文类型：学位论文

【摘要】：目的：探讨超声诊断原发性肾小球疾病的临床应用价值。方法：（1）首先超声诊断仪做二维超声扫查，然后再做彩色多普勒超声扫查应用脉冲多普勒技术（PW）测量段动脉的血流频谱参数，，连续测量多个心动周期血流频谱,取平均值（2）超声引导下肾穿刺活检，术后标本送病理做光镜，免疫荧光、电镜检查。结果：2.1、病理分型情况：由高到低依次为MSPGN、MN、IGAN。2.2临床分型情况：NS为34例，CGN为21例，AGN为10例。2.3、各组间肾脏的长径、宽径、厚径及实质厚度经统计学处理，C组、D组与A组之间，C组、D组与B组之间，D组与C组之间差异均有统计学意义（P0.05）。2.4、临床分期（A、B、C、D组）与2D-US分型、CDFI分型相比较，（P0.05），差异有统计学意义。2.5、段动脉血流频谱: C组、D组段动脉血流频谱RI与健康组比较，差异有统计学意义(P0.05)。结论：1、二维超声能直观提示氮质血症和尿毒症期。彩色多普勒超声能准确显示肾脏血流灌注情况和血流动力学变化，二者结合使用对原发性肾小球疾病患者的临床诊断和预后评估具有重大意义。2、2D-US及彩色多普勒超声对病理分型无实际意义，区分病理类型仍依赖肾组织病理活检。
[Abstract]:Objective: to evaluate the clinical value of ultrasound in the diagnosis of primary glomerular diseases. Then color Doppler echocardiography was performed to measure the blood flow spectrum parameters of segmental artery by using pulsed Doppler technique (PW). The blood flow spectrum of multiple cardiac cycles was measured continuously, and the average value was taken as 2) the renal puncture biopsy was guided by ultrasound. Results: pathological classification: from high to low was MSPGNN MNIGAN.2.2 Clinical classification of 34 cases with CGN was 34 cases, 21 cases with AGN were 10 cases with AGN, 10 cases with AGN, 10 cases with AGN, 10 cases with AGN, 10 cases with AGN, 10 cases with AGN, 10 cases with AGN, 10 cases with AGN, 10 cases with AGN, 10 cases with AGN. There were significant differences in thickness and parenchymal thickness between group D and group A between group D and group B, there were significant differences between group D and group C (P 0.05) and clinical stage (group D) and 2D-US classification of CDFI (there was a significant difference between group D and 2D-US), there was a significant difference between group D and group C (P > 0.05), and there was a significant difference between group D and group B (P < 0.05), and there was a significant difference between group D and group B (P < 0.05) and group C (P < 0.05). The spectral RI of segmental blood flow in group C and D was compared with that in healthy group. The difference was statistically significant (P 0.05). Conclusion: 1, 2 D ultrasound can directly indicate the stage of azotemia and uremia. Color Doppler ultrasound can accurately show the renal hemoperfusion and hemodynamic changes. The combination of the two methods is of great significance in the clinical diagnosis and prognosis evaluation of patients with primary glomerular disease. 2D-US and CDFI have no practical significance in pathological classification. The differentiation of pathological types still depends on renal biopsy.
【学位授予单位】：青海大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R445.1

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