3.0T磁共振DWI多b值及ADC值对囊型包虫病的应用研究

发布时间：2018-03-10 11:00

本文选题：囊型包虫　切入点：DWI多b值　出处：《青海大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:应用3.0T磁共振分析人体囊型包虫(CE)在扩散加权成像(DWI)不同b值的影像学表现和表观系数(ADC),选取最佳b值并探讨DWI序列及ADC值对CE分型的诊断效能。方法:收集2015年8月至2016年12月之间在我院确诊为CE患者54例,共113个病灶,行MRI常规呼吸触发SE序列、FFE序列及多梯度扩散因子(b值)DWI扫描,记录病灶在不同b值(80、300、500、800、1200、2000s/mm2)下DWI序列及ADC图的表现,测量病灶在不同b值下的ADC值及不同类型CE病灶在同一b值下的ADC值,并进行统计学分析。结果:1.所有病例组共计病灶113个,最大直径8.76±4.13cm,(2.04-26.71cm)。非肝脏组:肝脏组(40:73),二者最大直径与平均ADC值均无统计学差异(P0.05)。2.ADC值:随着b值的增大,CE病灶ADC值逐渐减低;b=800s/mm2对CE病灶显示较好。3.CE分型:单纯囊肿型及多子囊型各32个,内囊破裂型10个,实变钙化型33个,混合型6个。?以下五组病灶组间存在差异(P0.05),单纯囊肿型、多子囊型(子囊)与多子囊型(母囊)、实变钙化型有统计学差异(P0.05),多子囊型(母囊)与实变钙化型差异有统计学意义(P0.05),内囊破裂型与其他四组均无统计学差异(P0.05)。?混合型中的多子囊、实变钙化与多子囊型、实变钙化型均无统计学差异(P0.05)。结论:DWI序列及ADC值有助CE的诊断及其分型。五种类型CE病灶,其ADC值随着包虫囊肿活性的变化逐渐减低;生物学活性高的(单纯囊肿型、多子囊型的子囊)其ADC值较高;活性减低的(多子囊型的母囊、破裂型及实变钙化型)其ADC值较低;处于过渡阶段的(破裂型)其ADC值与其他各型均有重叠。
[Abstract]:Objective: to analyze the imaging manifestation and apparent coefficient of CEE in diffusion-weighted imaging (DWI) by using 3.0T magnetic resonance, select the best b value and discuss the diagnostic efficacy of DWI sequence and ADC value in CE typing. From August 2015 to December 2016, 54 cases of CE were diagnosed in our hospital. A total of 113 lesions were examined with MRI routine respiratory trigger SE sequence and multigradient diffusion factor (MGF). The DWI sequences and ADC images of the lesions were recorded under different b values (80 / 300 / 800 / 800 / 2000 / m2). The ADC values of lesions at different b values and the ADC values of different types of CE lesions at the same b value were measured and analyzed statistically. Maximum diameter 8.76 卤4.13 cm ~ (-1) 2.04 ~ 26.71 cm ~ (-1). Non-liver group: liver group: 40: 73, there is no significant difference between the maximum diameter and average ADC value (P0.05N. 2.ADCs): with the increase of b value, the ADC value of CE lesion decreases gradually. There are 32 multidaughter types each, Internal capsule rupture type 10 solid calcification type 33 mixed type 6.? In the following five groups, there was a difference between the two groups (P 0.05), and the type of cysts was simple. There was a significant difference between multiple oocyst type (daughter cyst) and multiple daughter cyst type (female cysts, solid calcification type) (P0.05), and there was significant difference between multiple daughter cyst type (mother cyst) and solid calcification type (P0.05). There was no significant difference between internal capsule rupture type and other four groups (P0.05. There was no significant difference between multiple, solid calcified and multiple daughter type in mixed type (P 0.05). Conclusion the ratio of ADC and ADC is helpful to the diagnosis and classification of CE, and five types of CE lesions. The ADC value decreased with the change of hydatid cyst activity, the ADC value was higher in those with high biological activity (simple cyst type, multiple daughter cyst type), lower ADC value in lower activity type (multiple daughter cyst type, ruptured type and solid calcification type). The ADC values of the transition (rupture type) are overlapped with other types.
【学位授予单位】：青海大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R445.2;R532.32

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