胎儿脑灰质异位的产前诊断及文献回顾

发布时间：2018-03-13 16:29

本文选题：脑灰质异位　切入点：产前诊断　出处：《南方医科大学学报》2015年12期 　论文类型：期刊论文

【摘要】：目的探讨胎儿大脑灰质异位(FGMH)的产前超声图像特征并评价其最佳产前诊断方法。方法对1例大脑灰质异位产前产后超声图像以及核磁共振图像进行分析,结合产前诊断该病的相关文献进行回顾性分析,比较产前超声及MRI对FGMH的检出率。结果总结1998~2015年文献11篇,结合本文报道1例,产前诊断灰质异位44例,经活产或引产后证实且有产前超声和产前MRI资料者32例,其中超声检出率43.8%,MRI检出率93.8%,二者检出率比较差异有统计学意义(P0.001)。结论只有室管膜下型大脑灰质异位才有可能为产前超声所发现,其他类型主要依靠MRI。MRI是FGMH最佳产前诊断方法,当产前超声提示灰质异位时都应进一步行MRI检查。
[Abstract]:Objective to investigate the characteristics of prenatal ultrasound images of fetal gray matter ectopic FGMH and to evaluate the best prenatal diagnosis method. Methods A case of cerebral gray matter ectopic pre- and post-natal ultrasound images and magnetic resonance imaging were analyzed. The detection rate of FGMH by prenatal ultrasound and MRI was compared with that of prenatal diagnosis. Results from 1998 to 2015, 11 articles were summarized, 1 case was reported and 44 cases were diagnosed by prenatal diagnosis of gray matter ectopic. 32 cases were confirmed by live birth or induced labor and had prenatal ultrasound and prenatal MRI data. Among them, the detectable rate of ultrasound was 43.8% and the detectable rate of MRI was 93.8.The difference between them was statistically significant (P 0.001). Conclusion only subependymal cerebral gray matter heterotopia can be detected by prenatal ultrasound, and other types mainly depend on MRI.MRI as the best prenatal diagnosis method for FGMH. Further MRI examination should be performed when prenatal ultrasound indicates ectopic gray matter.
【作者单位】：南方医科大学附属深圳市妇幼保健院超声科;
【基金】：国家自然资金科学基金(60671043) 国家科技支撑计划(2014BAI06B05)~~
【分类号】：R714.5;R445.1

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