基于增强CT扫描成像的灰度共生矩阵纹理分析不同T分期食管鳞状细胞癌

发布时间：2018-03-13 20:30

本文选题：食管鳞状细胞癌　切入点：增强CT　出处：《临床放射学杂志》2017年09期 　论文类型：期刊论文

【摘要】：目的探究提取增强CT图像的灰度共生矩阵纹理参数的方法分期食管鳞状细胞癌的可行性。方法选取本院36例经内镜活检病理确诊的食管鳞状细胞癌患者36例,在采取治疗方案之前,行胸、腹部CT增强扫描。两位资深CT诊断医师将患者增强CT图像导入Omni-kinetics软件对肿瘤组织进行勾画。勾画完成后,使用OmniKinetics软件进行纹理参数计算。结果随着T分期的增加,Energy值降低,且不同T分期的Energy差异具有统计学意义(P=0.001);随着T分期的增加,Entropy值升高,且不同T分期的Entropy差异具有统计学意义(P=0.007);随着T分期的增加,IDM值逐渐变小,且不同分期的IDM值具有统计学意义(P=0.000)。T1期Energy值的95%置信区间为(0.037,0.052),T2期Energy值的95%置信区间为(0.009,0.035),T3期Energy值的95%置信区间为(0.002,0.007);T1期Entropy值的95%置信区间为(4.104,4.562),T2期Entropy值的95%置信区间为(4.577,4.926),T3期Entropy值的95%置信区间为(5.001,5.221);T1期IDM值的95%置信区间为(0.019,0.027),T2期IDM值的95%置信区间为(0.011,0.014),T3期IDM值的95%置信区间为(0.003,0.010)。结论基于增强CT扫描成像的灰度共生矩阵纹理分析分期食管鳞状细胞癌的方法具有一定价值,未来可尝试作为建立食管鳞状细胞癌分期鉴别的无侵入性方法。
[Abstract]:Objective to explore the feasibility of extracting grayscale co-occurrence matrix texture parameters of enhanced CT images for staging esophageal squamous cell carcinoma. Methods 36 patients with esophageal squamous cell carcinoma confirmed by endoscopic biopsy were selected. Before the treatment, chest and abdomen CT enhanced scans were performed. Two senior CT diagnostics imported enhanced CT images of patients into Omni-kinetics software to outline the tumor tissue. OmniKinetics software was used to calculate the texture parameters. Results with the increase of T stage, the energy value decreased, and the difference of Energy between different T stages was statistically significant, and the Entropy value increased with the increase of T stage. The difference of Entropy in different T stages was statistically significant (P < 0. 007). And the IDM value of different stages is statistically significant. The 95% confidence interval of Energy value in stage T 1 is 0.037 / 0.052 / T 2 Energy value 95% confidence interval is 95% confidence interval of Energy value in stage 0. 009 / 0. 035 / T _ 3 / T _ 3 and the 95% confidence interval of Entropy value in T _ 1 period is 4. 104 / 4. 562T _ 2 and 95% confidence interval of Entropy value in T _ 2 period. The 95% confidence interval of Entropy value in T _ 3 phase is 5.001 / 5.221 / T _ 1 / T _ 1 and the 95% confidence interval in T _ 1 is 0.019 / 0.027 / T _ 2 / T _ 2 IDM / T _ 2 / T _ 2 IDM / T _ 2 / T _ 2 / T _ 2 / T _ 2 / T _ 3 / T _ 3 / T _ 3 / T _ 3 / T _ 3 / T _ 3 / T _ 3 / T _ 3 / T _ 3 / T _ 3 / T _ 3 / T _ 3 / T _ 3 / T _ 3 / T _ 3 / T _ 3 / T _ 3 / T _ 3 / T _ 3. The method of tubular squamous cell carcinoma has some value. In the future, we may try to establish a non-invasive method for the differentiation of esophageal squamous cell carcinoma.
【作者单位】：湖北省黄冈市中心医院医学影像科;
【分类号】：R730.44;R735.1

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