血管回声跟踪技术评价头颈部肿瘤患者放疗后颈动脉弹性

发布时间：2018-03-16 14:32

本文选题：头颈部肿瘤　切入点：颈动脉　出处：《中国临床医学影像杂志》2015年06期 　论文类型：期刊论文

【摘要】：目的:应用E-Tracking技术探讨头颈部肿瘤患者放疗后颈动脉弹性功能变化及其临床意义。方法:收集75例放疗后头颈部肿瘤患者(放疗组)及65例健康志愿者(对照组),比较两组颈动脉的参数变化;选择放疗组39例患者比较放疗前与放疗后的颈动脉参数变化;E-Tracking参数包括僵硬度(β)、弹性模型(Eρ)、顺应性(AC)、脉搏波传导速度(PWVβ)及内-中膜厚度(IMT)。并对放疗组颈动脉损伤影响因素进行分析。结果:放疗组较对照组β、Eρ、PWVβ、IMT升高,AC降低,差异均有统计学意义(P0.05)。与放疗前比较,放疗后β、Eρ、PWVβ值增高,AC降低,差异有显著性(P0.05),IMT比较无显著性差异(P0.05)。经多因素Logistic回归分析发现年龄60岁、放疗间隔时间5年是头颈部肿瘤患者放疗后颈动脉损伤的危险因素。结论 :头颈部肿瘤患者放疗后颈动脉弹性功能较正常人减低;E-Tracking参数能够早期反映颈动脉弹性功能的异常改变;年龄、放疗间隔时间是头颈部肿瘤患者放疗后颈动脉损伤的危险因素。
[Abstract]:Objective: to investigate the changes of carotid elastic function and its clinical significance in patients with head and neck neoplasms after radiotherapy with E-Tracking technique. Methods: 75 patients with head and neck tumors (radiotherapy group) and 65 healthy volunteers (control group) after radiotherapy were collected. To compare the changes of carotid artery parameters between the two groups. Thirty-nine patients in the radiotherapy group were selected to compare the changes of carotid artery parameters before and after radiotherapy. The parameters of E-Tracking included stiffness (尾), elastic model E 蟻, compliance, pulse wave velocity (PWV 尾) and IMTT. Results: compared with the control group, the 尾 -E 蟻 PWV 尾 -IMT in the radiotherapy group was higher than that in the control group, and the AC was lower in the radiotherapy group than in the control group. The difference was statistically significant (P 0.05). Compared with before radiotherapy, the value of 尾 E 蟻 PWV 尾 increased and AC decreased after radiotherapy, but there was no significant difference between them (P 0.05). The age of 60 years old was found by multivariate Logistic regression analysis. The interval of 5 years was the risk factor of carotid artery injury in patients with head and neck tumors after radiotherapy. Conclusion: the reduced elastic function of carotid artery in patients with head and neck tumors after radiotherapy can reflect carotid elasticity early compared with normal people. Abnormal changes of sexual function; Age and radiotherapy interval were risk factors of carotid artery injury in patients with head and neck tumor after radiotherapy.
【作者单位】：大连医科大学附属第二医院;
【分类号】：R739.91;R445.1

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