彩色多普勒感兴趣区定量技术评价肾病综合征患者肾皮质血流灌注

发布时间：2018-03-19 03:16

本文选题：肾病综合征　切入点：超声检查　出处：《中国医学影像学杂志》2017年02期 　论文类型：期刊论文

【摘要】：目的探讨彩色多普勒感兴趣区(ROI)定量技术评价肾病综合征(NS)患者肾皮质血流灌注状态的应用价值。资料与方法收集华中科技大学同济医学院附属协和医院2014年9月—2015年1月收治的21例原发性NS患者作为病例组,另纳入29名性别、年龄匹配的健康志愿者为对照组。应用PhilipsiU22超声诊断仪采集所有受检者左肾中部高帧频彩色血流动态图像。测量叶间动脉、弓形动脉和小叶间动脉阻力指数(RI);Q-LAB工作站定量分析ROI内肾皮质血流灌注的各项指数,包括血管指数(VI)、血流指数(FI)和血管血流指数(VFI)。结果 1对照组肾皮质内血流信号连续,多可达皮质边缘;NS患者肾皮质内血流信号稀疏,血流束纤细;2与对照组比较,病例组患者肾叶间动脉、小叶间动脉RI测值差异均无统计学意义(P0.05);3 NS患者肾脏血流灌注明显减低,肾皮质VI、FI、VFI测值均减低,差异有统计学意义(P0.01);4一致性分析显示,VI、FI、VFI测值重复性良好。结论彩色多普勒ROI定量技术评价肾皮质血流灌注准确可行,可为临床早期明确肾损害提供新依据。
[Abstract]:Objective to evaluate the value of color Doppler ROI quantitative technique in evaluating renal cortical perfusion status in patients with nephrotic syndrome (NSN). Data and methods data and methods collected from Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, 2014. From June to January 2015, 21 patients with primary NS were treated as the case group. In addition, 29 healthy volunteers with gender and age matching were included as control group. Dynamic images of high frame color blood flow in the middle of left kidney were collected by PhilipsiU22 ultrasound diagnostic instrument. The interlobar artery was measured. The resistance index of arcuate artery and interlobular artery was determined by RII-Q-lab workstation for quantitative analysis of various indexes of renal cortex perfusion in ROI, including vascular index (VII), blood flow index (FII) and vascular flow index (VFI). Results 1 the blood flow signals in the renal cortex of the control group were continuous. Compared with the control group, the RI of renal interlobar artery and interlobular artery in the case group were not significantly lower than those in the control group. The VFI values of renal cortex were all decreased, and the difference was statistically significant (P 0.01). The results showed that the VFI values were reproducible and reproducible. Conclusion Color Doppler ROI quantitative evaluation of renal cortex perfusion is accurate and feasible. It can provide a new basis for early diagnosis of renal damage.
【作者单位】：华中科技大学同济医学院附属协和医院超声影像科;
【分类号】：R445.1;R692

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