全身成像三维量化法评估二尖瓣反流严重程度的可行性及准确性

发布时间：2018-03-21 23:05

本文选题：超声心动描记术　切入点：三维　出处：《中国循环杂志》2017年07期 　论文类型：期刊论文

【摘要】：目的:探讨全身成像三维量化(GI3DQ)法测量的二尖瓣反流束体积(MRvol)评估二尖瓣反流(MR)严重程度的可行性及准确性。方法:93例MR患者根据二尖瓣反流束方向分为两组:中心性MR组41例,偏心性MR组52例。依据实时三维超声心动图(RT3DE)平面法测量MR的有效反流口面积(EROA)将MR患者分为轻度、中度、重度。GI3DQ法直接测量MRvol。结果:中心性MR组受试者工作特征(ROC)曲线分析示:GI3DQ法测量的MRvol16.2 ml时,曲线下面积为0.93(P0.0001),区分轻度MR和中度MR的敏感性为96.0%、特异性为70.0%;MRvol44.5 ml时,曲线下面积为0.96(P0.0001),区分中度MR和重度MR的敏感性为97.6%、特异性为91.7%。偏心性MR组ROC曲线分析示:MRvol14.2 ml时,曲线下面积为0.77(P=0.0243),区分轻度MR和中度MR的敏感性为91.8%、特异性为62.5%;MRvol40.5 ml时,曲线下面积为0.83(P0.0001),区分中度MR和重度MR的敏感性为82.3%、特异性为77.9%。结论:以RT3DE平面法测量MR的EROA为参考标准,GI3DQ法直接测量MRvol可较为准确地评估MR的严重程度,尤其在中心性MR组,区分中度MR和重度MR时,拥有更高的敏感性和特异性。
[Abstract]:Objective: to investigate the feasibility and accuracy of evaluating the severity of mitral regurgitation (MRV) by GI3DQM. Methods: according to the direction of mitral regurgitation, 93 cases of Mr were divided into two groups. Central Mr group (41 cases), The effective reflux area (EROAA) of Mr was measured by real time three-dimensional echocardiography (RT3DE) plane method in 52 patients with eccentric Mr. Results: in the central Mr group, the analysis of the operating characteristics of the subjects showed that the area under the curve was 0.93GI3DQ, and the sensitivity was 96.0ml for mild and moderate Mr, and the specificity was 70.01ml for MRvol.Results: the results showed that the area under the curve was 0.93GI3DQ, the sensitivity was 96.0ml, and the specificity was 70.01ml. The area under the curve was 0.96 g P0.0001g, and the sensitivity and specificity were 97.6g and 91.7 respectively. The area under the curve was 0.77g / ml, and the sensitivity was 91.8ml for mild and moderate Mr, and the specificity was 62.5mol / ml for moderate and moderate Mr, respectively. The ROC curve analysis of eccentric Mr group showed that the area under the curve was 0.77g / v 0.0243ml, and the sensitivity was 91.8ml for mild and moderate Mr, and the specificity was 62.5ml for MRvol40.5 ml. The area under the curve is 0.83g P0.0001g, the sensitivity of differentiating moderate and severe Mr is 82.3 and the specificity is 77.9.Conclusion: using EROA of RT3DE plane method as the reference standard, direct measurement of MRvol by GI3DQ can evaluate the severity of Mr more accurately, especially in the group of central Mr. There is a higher sensitivity and specificity in differentiating moderate and severe Mr.
【作者单位】：青岛大学附属医院心脏超声科;中国医学科学院北京协和医学院国家心血管病中心阜外医院超声科;
【分类号】：R540.45;R542.51

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