急性Ⅰ型单纯疱疹病毒感染性脑炎影像学表现

发布时间：2018-03-22 07:43

本文选题：急性Ⅰ型单纯疱疹病毒　切入点：感染　出处：《中华医院感染学杂志》2015年23期 　论文类型：期刊论文

【摘要】：目的探讨急性Ⅰ型单纯疱疹病毒性脑炎(Herpes Simplex Virus Encephalitis,HSE)不同病理机制多种影像学表现,以提高治愈率。方法回顾性分析2003-2013年16例确诊HSE有脑出血病灶的患者临床资料,对其进行影像学检查,16例HSE患者均先行CT检查,根据病情其中有7例患者行MRI检查,对影像学的多种重要表现结合文献进行分析总结。结果 HSE患者发病早期30min~2h在CT影像上基底节密度稍增高,基底节突出显示,即"基底节突显征";发生于基底节、脑灰质及灰白质交界区的细微小灶状、小疱疹样出血,具有一定的典型意义;发生于颞叶脑白质病变多呈水肿、变性样改变,CT上低密度、MRI上呈长T1长T2信号,多发生于颞叶而基底节未受累呈现"刀切征",则是公认的较为典型征像。结论影像诊断多种检查技术联合应用,总结出单纯疱疹病毒(HSV)感染所致HSE的影像的一些特征性表现,对HSE患者影像诊断、特别是早期诊断具有重要意义,对降低HSE患者的病死率及致残率有一定价值。
[Abstract]:Objective to investigate the various imaging manifestations of Herpes Simplex Virus Encephalitis (HSE) in acute herpes simplex encephalitis (HSE) in order to improve the cure rate. Methods the clinical data of 16 patients with intracerebral hemorrhage in HSE from 2003 to 2013 were analyzed retrospectively. All the 16 cases of HSE were examined by CT, and 7 of them were examined by MRI according to their condition. Results in the early stage of HSE, the density of basal ganglia increased slightly, and the basal ganglia protruded, that is, "prominent sign of basal ganglia", occurred in basal ganglia. The small focus of gray matter and the junction of gray matter and white matter, herpes zoster haemorrhage, have typical significance, the white matter lesions in temporal lobe are mostly edema, degenerative changes show long T 1 and long T 2 signal on low density MRI on CT. Most of the lesions occurred in temporal lobe without involvement of basal ganglia, which were generally recognized as typical signs. Conclusion combined use of multiple imaging diagnostic techniques, some characteristic features of HSE caused by herpes simplex virus (HSV) infection are summarized. It is of great significance for the imaging diagnosis of HSE, especially for early diagnosis. It is valuable to reduce the mortality and disability rate of HSE patients.
【作者单位】：宁波第七医院影像中心;宁波明州医院影像中心;浙江医院ICU;
【基金】：浙江省医药卫生平台骨干人才计划基金资助项目(2012RCA001)
【分类号】：R512.39;R816.1;R445.2

【相似文献】