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急性胰腺炎胰周血管受累的MRI表现

发布时间:2018-03-23 00:08

  本文选题:急性胰腺炎 切入点:磁共振成像 出处:《川北医学院》2014年硕士论文 论文类型:学位论文


【摘要】:目的:探讨急性胰腺炎(Acute pancreatitis,,AP)胰周血管受累的磁共振表现、发生率;胰周血管受累与急性生理慢性健康评分系统Ⅱ(AcutePhysiology And Chronic Healthy Evaluation Ⅱ,APACHⅡ)、磁共振严重指数(Magnetic Resonance severity index,MRSI)的相关性研究。 材料和方法:收集本院2009年8月至2013年8月期间326例AP患者资料,其中男161例,女165例,年龄17-88岁,平均(53±15)岁。所有病例均签署知情同意书。AP患者均在住院后3天内行腹部平扫加增强检查,其中122例AP患者采用GE1.5T MR扫描,204例采用GE3.0TMR扫描,序列包括:横断面脂肪抑制梯度回波T1加权、横断面快速恢复快速自旋回波呼吸门控抑脂T2加权、冠状面及横断面单次激发快速自旋回波T2加权、单次激发快速自旋回波胰胆管成像、动态增强检查采用抑脂三维肝脏容积快速采集。观察AP的MRI表现,行MRSI评分,0-3分为轻度,4-6分为中度,7-10分为重度。根据患者临床资料做APACHⅡ评分,小于8分为轻症AP,大于(或等于)8分为重症AP。观察AP的胰周血管异常表现,胰周血管包括脾静脉、脾动脉、肠系膜上动脉、肠系膜上静脉、门静脉、腹腔干、肝总动脉及分支,异常改变包括动脉受侵(炎症)、假性动脉瘤,静脉受侵(炎症)、静脉血栓、胰源性门静脉高压等。用Spearman法统计分析血管并发症与MRSI、APACHⅡ评分的相关性。 结果:326例AP患者中,急性间质水肿型AP267例,占81.9%,急性坏死性AP59例,占18.1%。根据MRSI评分,轻、中、重度分别为38%(124/326)、55%(180/326)、7%(22/326)。16.9%(55/326)的AP患者至少出现一项胰周血管并发症。12%(32/267)的急性间质性AP患者发生胰周血管并发症,39%(23/59)的坏死性AP患者发生胰周血管并发症,二者之间的差异具有统计学意义(P<0.05)。轻度、中度、重度AP患者胰周血管并发症发生率分别为3%(4/124)、17%(31/180)、91%(20/22)。其中脾静脉血栓7例、肠系膜上静脉血栓5例、脾动脉受侵(炎症)47例、脾静脉受侵(炎症)49例,以上血管并发症在MRSI评分轻、中、重度患者中发生率差异具有统计学意义,并与MRSI评分呈正相关(P<0.05,0.3<r<0.5);腹腔干受侵(炎症)10例、门静脉受侵(炎症)23例、肝总动脉受侵(炎症)16例、肠系膜上动脉受侵(炎症)36例、肠系膜上静脉受侵(炎症)24例,以上并发症在MRSI评分轻、中、重度患者中发生率差异具有统计学意义,但与MRSI评分无明显相关性(P<0.05,r<0.3);门静脉血栓4例、脾动脉假性动脉瘤3例,其发生率差异不具有统计学意义,与MRSI评分也无明显相关性(P>0.05,r<0.3)。另有胰源性门静脉高压2例。326例AP患者的APACHEⅡ分数为0-23分,平均5.80±4.620,238例为轻症AP,88例为重症AP,14%(34/238)的轻症患者出现胰周血管并发症,24%(21/88)的重症患者出现胰周血管并发症,二者之间的差异具有统计学意义,与急性生理慢性健康评分Ⅱ无相关性(r=0.114,P<0.05)。 结论:AP的胰周血管并发症较为常见,包括门静脉血栓、脾静脉血栓、肠系膜上静脉血栓、脾动脉假性动脉瘤、门静脉炎症、肠系膜上静脉炎症、脾静脉炎症、脾动脉炎症、肠系膜上动脉炎症、肝总动脉炎症、腹腔干炎症、胰源性门静脉高压等,其中脾静脉血栓、脾动静脉炎症、肠系膜上静脉血栓与急性胰腺炎的严重程度呈正相关,可以作为一个早期预测AP严重程度的指标。急性胰腺炎胰周血管并发症与APACHEⅡ评分没有明显相关性。
[Abstract]:Objective: To study the acute pancreatitis (Acute, pancreatitis, AP) incidence rate of MRI, peripancreatic vascular involvement; peripancreatic vascular involvement and acute physiology and chronic health evaluation II (AcutePhysiology And Chronic Healthy Evaluation II, APACH II), magnetic resonance (Magnetic Resonance severity index severity index, MRSI) studies.
Materials and methods: collected in our hospital from August 2009 to August 2013 326 cases of AP patients, male 161 cases, female 165 cases, age 17-88 years, average (53 + 15) years old. All patients signed the informed consent.AP patients were in hospital within 3 days of abdominal plain and enhanced scan, 122 cases AP patients with GE1.5T MR scan, 204 cases by GE3.0TMR scan, including sequence: cross sectional gradient echo T1 weighted fat suppression, cross-sectional fast recovery fast spin echo T2 weighted fat suppressed respiratory gating, coronal and axial single shot fast spin echo T2 weighted fast spin echo imaging, dynamic contrast-enhanced examination by fat suppressed 3D liver volume rapid acquisition. To observe the AP MRI expression, MRSI score, 0-3 points to 4-6 points for the mild, moderate, 7-10 were severe. According to the clinical data of patients with APACH score less than 8, divided into mild AP, big In (or equal to) 8 divided into severe AP. observation of peripancreatic vessels AP abnormalities, peripancreatic vessels including splenic vein and splenic artery, superior mesenteric artery, superior mesenteric vein, portal vein, hepatic artery and celiac trunk, branches, abnormal changes including arterial involvement (Yan Zheng), pseudoaneurysm, vein invasion (Yan Zheng), venous thrombosis, pancreatogenous portal hypertension. Spearman with the method of statistical analysis and MRSI correlation of vascular complications, APACH score.
缁撴灉锛

本文编号:1651010

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