恶性肺上叶后段占位性病变CT良性影像表现的相关研究

发布时间：2018-03-27 09:38

本文选题：肺上叶后段占位　切入点：CT影像表现　出处：《首都医科大学学报》2017年04期

【摘要】：目的探究恶性肺上叶后段占位性病变电子计算机断层扫描(computed tomography,CT)良性表现的危险因素,为临床诊断提供理论依据。方法回顾性研究首都医科大学宣武医院及首都医科大学附属北京友谊医院平谷医院胸外科2011年1月1日至2016年12月31日肺上叶后段占位性病变CT良性表现病人139例。计算各年份恶性肺上叶后段占位性病变CT良性影像表现的发生率;对比病人的各项临床资料,并采用Logistic回归分析危险因素。结果各年恶性肺上叶后段占位性病变CT良性影像表现的发生率分别为8.33%、11.11%、19.05%、26.92%、34.38%、40.00%;Logistic回归显示:年龄、吸烟、右位病变、单光子弥散计算机断层成像术(single-photon emission computed tomography,SPECT)放射凝聚征阳性、癌胚抗原(carcino-embryonic antigen,CEA)、细胞角蛋白19片段21-1(cytokeratin protein fragment 21-1,CYFRA21-1)及神经元特异性烯醇化酶(neuron specific enolase,NSE)异常,为恶性肺上叶后段占位性病变CT良性表现的危险因素,OR(95%CI)分别是1.123(1.038~1.215)、5.951(1.778~9.919)、3.547(1.104~10.397)、3.565(1.096~11.598)、18.638(4.974~29.843)、7.357(2.265~13.010)、7.639(3.107~14.697)。结论恶性肺上叶后段占位性病变CT良性影像表现的发生率较高,值得重视;危险因素为老龄、吸烟、右位病变、SPECT放射凝聚征阳性及肺癌相关肿瘤标志物异常,临床医师需谨慎对待,早发现、早治疗,以提高病人生存率。
[Abstract]:Objective to investigate the risk factors of benign manifestations of malignant upper lobe space occupying lesions in computed tomography CT (CT). Methods retrospective study on chest surgery in Pinggu Hospital, Xuanwu Hospital, Capital Medical University and Pinggu Hospital, Beijing Friendship Hospital affiliated to Capital Medical University from January 1, 2011 to December 31, 2016. The incidence of benign CT findings of malignant posterior segment of the upper lobe was calculated in 139 patients with benign CT findings. The clinical data of the patients were compared, and the risk factors were analyzed by Logistic regression analysis. Results the incidence of benign CT imaging manifestations of the malignant posterior segment of the upper lobe of the lung was 8.33 and 11.11 and 19.05 respectively. Logistic regression showed that age, smoking, right position lesions, and so on. Single-photon emission computed tomography-SPECT was positive, carcinoembryonic antigen carcinoembryonic antigen CEA, cytokeratin 19 fragment 21-1(cytokeratin protein fragment 21-1 CYFRA21-1 and neuron specific enolase specific enolase NSEs were abnormal. The risk factors for benign CT findings of malignant upper posterior lobe space occupying lesions were 1.123 / 1.0381.215A 5.9511.7789.919 / 3.5471.1047 / 1.1047 / 10.3971.5651.1.0969.59818.6384.9744 / 29.843 7.3572.26513.0107.6397.6397.6395.Conclusion the incidence of benign CT findings in the malignant posterior segment of the lung is higher than that of the controls, and the risk factors are elderly, smoking, smoking, and the risk factors are as follows: (1) the incidence of benign CT findings in the malignant posterior segment of the upper lobe of the lung is higher than that in the control group, and the risk factors are elderly, smoking, smoking, and the risk factors are as follows: (1) the incidence of benign CT findings in the posterior segment of the upper lobe of the malignant lung is higher than that in the control group, and the risk factors are elderly, smoking, and smoking. In order to improve the survival rate of patients with right lesions, the positive SPECT radiation coagulation sign and the abnormal tumor markers associated with lung cancer should be treated carefully, detected early and treated early.
【作者单位】：首都医科大学附属北京友谊医院平谷医院胸外科;首都医科大学宣武医院胸外科;
【分类号】：R730.44;R734.2

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