钆塞酸二钠和钆喷酸葡胺肝脏多期动态增强呼吸伪影对比研究

发布时间：2018-03-29 04:34

本文选题：磁共振成像　切入点：钆塞酸二钠　出处：《放射学实践》2015年01期

【摘要】：目的:比较静脉注射钆塞酸二钠(Gd-EOB-DTPA)和钆喷酸葡胺(Gd-DTPA)的动脉期呼吸伪影,寻求减少Gd-EOB-DTPA动脉期呼吸伪影的可能方案。方法:搜集在1年内行Gd-EOB-DTPA和Gd-DTPA磁共振动态增强扫描的患者75例,由两位有经验的磁共振医师采用盲法对两种对比剂扫描方案的动脉期、门脉期及延迟期图像采用5分法评分,以≤3分定义为中重度伪影。两种对比剂扫描方案的呼吸伪影比较采用Wilcoxon秩和检验和配对卡方检验。结果:Gd-EOB-DTPA组发生动脉晚期呼吸伪影的比例明显高于Gd-DTPA组(分别为49.3%和6.7%,Z=-5.058,P0.001),其中中重度伪影的比例亦明显高于Gd-DTPA(分别为33.33%和2.67%,χ2=21.04,P0.001);而Gd-EOB-DTPA组动脉早期出现呼吸伪影和中重度呼吸伪影的比例与Gd-DTPA组差异无统计学意义(Z=-1.513,P=0.130;χ2=0.25,P=0.625)。结论:静脉注射Gd-EOB-DTPA较Gd-DTPA更易引起动脉期伪影,减少单期屏气时间和采用动脉期监测技术可能提高Gd-EOB-DTPA动脉期采集的图像质量。
[Abstract]:Objective: to compare the arterial phase respiration artifacts of intravenous injection of Gd-EOB-DTPA and Gd-DTPA, and to explore a possible scheme to reduce the arterial phase respiratory artifacts of Gd-EOB-DTPA. Methods: 75 patients who underwent Gd-EOB-DTPA and Gd-DTPA dynamic enhanced magnetic resonance imaging within one year were collected, and the results were compared with that of Gd-DTPA-Gd-DTPA-Gd-EOB-DTPA-Gd-EOB-DTPA-Gd-EOB-DTPA-Gd-EOB-DTPA. Two experienced magnetic resonance physicians scored the arterial phase, portal phase and delayed phase images of the two contrast media scanning schemes by a blind method with a 5-point method. Wilcoxon rank sum test and paired chi-square test were used to compare the respiratory artifacts of the two contrast agent scanning schemes. Results the proportion of late arterial respiratory artifacts in the group of 10% Gd-EOB-DTPA was significantly higher than that in the group of Gd-DTPA (respectively). The proportion of moderate to severe artifacts was significantly higher than that of Gd-DTPA (33.33% and 2.67%, 蠂 ~ 2 = 21.04 P 0.001, respectively, respectively), but there was no significant difference between Gd-EOB-DTPA group and Gd-DTPA group in the incidence of early respiratory artifacts and moderate and severe respiratory artifacts. Conclusion: Gd-EOB-DTPA was injected intravenously with Gd-EOB-DTPA 0.62%. Conclusion: there is no significant difference in the proportion of early and moderate and severe respiratory artifacts between Gd-EOB-DTPA group and Gd-DTPA group (P = 0.130; 蠂 2 = 0.25, P 0.625, respectively). Conclusion: there is no significant difference between Gd-EOB-DTPA group and Gd-DTPA group in the early occurrence of respiratory artifacts and moderate and severe respiratory artifacts in Gd-DTPA group. Conclusion: intravenous injection of Gd-EOB-DTPA has no significant difference in the proportion of early and moderate to severe respiratory artifacts in Gd-DTPA group. Arterial phase artifacts are more likely to occur than Gd-DTPA, Reducing the time of single phase breath-holding and using arterial phase monitoring may improve the image quality of Gd-EOB-DTPA arterial phase acquisition.
【作者单位】：北京协和医学院中国医学科学院肿瘤医院影像诊断科;
【分类号】：R445.2;R575

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