三维斑点追踪成像评价亚临床甲状腺功能减退女性治疗前后左心室整体收缩功能

发布时间：2018-04-01 00:35

本文选题：甲状腺功能减退症　切入点：超声心动描记术　出处：《中国医学影像学杂志》2015年06期

【摘要】：目的应用三维斑点追踪成像(3D-STI)技术评价亚临床甲状腺功能减退(SHT)女性患者行左旋甲状腺激素治疗前后左心室整体收缩功能的改变。资料与方法收集研究组32例SHT女性患者及对照组40例健康女性志愿者,研究组给予左旋甲状腺激素治疗,待甲状腺功能达到正常状态后随访1年;两组均行血生化检查、常规超声心动图检查和3D-STI检查,比较两组左心室舒张末期内径(LVEDd)、左心室收缩末期内径(LVEDs)、室间隔舒张末期厚度(IVSd)、左心室后壁舒张末期厚度(LVPWd)、左心房内径(LAD)、二尖瓣口舒张期血流频谱A峰值、左心室舒张末期容积(LVEDV)、左心室收缩末期容积(LVESV)、左心室射血分数(LVEF),分析三维左心室整体纵向应变(GLS)、整体圆周应变(GCS)、整体径向应变(GRS)及整体面积应变(GAS)参数以及促甲状腺激素(TSH)水平与各参数的相关性。结果治疗前研究组IVSd、LVPWd较对照组增加(t=3.30、3.64,P0.05),研究组治疗前二尖瓣口舒张期血流频谱E峰速度及E/A均小于对照组及研究组治疗后(t=13.55、13.85、3.19、2.93,P0.05)。研究组治疗前左心室GLS、GCS、GRS及GAS显著低于对照组(t=8.60、11.95、9.78、5.92,P0.05)。研究组治疗后左心室GLS、GCS、GRS及GAS均高于治疗前(t=6.91、9.41、6.46、4.31,P0.05)。TSH水平与E/A比值、E呈负相关(r=-0.39、-0.42,P0.05);TSH水平与GLS、GCS、GRS及GAS呈负相关(r=-0.38、-0.56、-0.33、-0.41,P0.05)。结论利用3D-STI可以较好地评价SHT女性患者左旋甲状腺激素治疗前后左心室整体收缩功能变化。
[Abstract]:Objective to evaluate the changes of global left ventricular systolic function in female patients with subclinical hypothyroidism before and after treatment with levothyroxine by using 3D-STI technique. Data and methods 32 cases of SHT in study group were collected. Female patients and 40 healthy female volunteers in the control group, The study group was treated with levothyroid hormone and followed up for one year after the thyroid function reached normal state. Both groups were given blood biochemical examination, routine echocardiography and 3D-STI examination. The left ventricular end-diastolic diameter (LVEDdN), left ventricular end-systolic diameter (LVEDs1), interventricular septal diastolic thickness (IVSdN), left ventricular posterior wall diastolic thickness (LVPWdN), left atrial diameter (lad), mitral valve diastolic frequency spectrum A (A) were compared between the two groups. Left ventricular end-diastolic volume (LVEDVV), left ventricular end-systolic volume (LVESVV), left ventricular ejection fraction (LVEF), and left ventricular ejection fraction (LVEF). Results before treatment, the LVPWd of IVSdT in the study group increased 3.30 ~ 3.64 渭 g P0.05 compared with the control group, and the E peak velocity and E / A of diastolic phase of mitral valve in the study group were lower than that in the control group and the study group after treatment, and the E peak velocity and E / A were lower than that in the control group and the study group after treatment. The GCS GRS and GAS of the left ventricle in the study group before treatment were significantly lower than those in the control group (8.6011.95,9.785.92). After treatment, the GCSGRS and GAS of the left ventricle in the study group were significantly higher than those before the treatment. Conclusion it is better to use 3D-STI to make use of 3D-STI. Objective to evaluate the changes of global left ventricular systolic function before and after left thyroid hormone therapy in female patients with SHT.
【作者单位】：辽宁医学院附属第一医院超声科;锦州石化医院超声科;
【分类号】：R581.2;R445.1

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