声触诊组织定量技术对慢性肾脏病分期的价值

发布时间：2018-04-03 19:30

本文选题：慢性肾脏病　切入点：声触诊组织定量　出处：《实用医学杂志》2017年14期

【摘要】：目的探讨声触诊组织定量(VTQ)技术在慢性肾脏病(CKD)分期中的应用价值。方法随机选取不同临床分期的CKD患者96例及健康志愿者(对照组)45例行VTQ检查,测量肾实质剪切波传播速度(SWV)并进行比较,分析CKD患者肾实质SWV测值与临床分期、肾小球滤过率(GFR)的相关性。结果随着病程分期进展、肾功能损害加重,肾实质SWV值逐渐减小。CKD组各期与对照组SWV的比较,对照组与CKD1期组(P=0.061)、CKD2期组与CKD3期组(P=0.238)、CKD4期组与CKD5期组(P=0.624)之间差异无统计学意义(P0.05),余各组两两比较,SWV值差异均具有统计学意义(P0.05);肾实质SWV值与CKD临床分期呈负显性相关(r=-0.65,P0.001),即CKD分期越高,SWV值越低;SWV值与GFR呈正相关关系(r=0.73,P0.001),即GFR越低,SWV值越低。结论 VTQ技术可以无创地反映肾实质的弹性变化,评价CKD患者肾功能损害程度,为CKD的临床分期提供了一种新的定量评估指标。
[Abstract]:Objective to explore the value of virtual touch tissue quantification (VTQ) technique in patients with chronic kidney disease (CKD) application value in staging. Methods 96 cases of different clinical stages of CKD patients and healthy volunteers were randomly selected (control group) and 45 patients underwent VTQ examination, measurement of renal parenchyma shear wave velocity (SWV) and compare analysis of patients with renal CKD the essence of SWV measurement and clinical staging, glomerular filtration rate (GFR). The correlation with disease stage progress, renal function impairment of renal parenchymal SWV decreased in.CKD group in each period compared with the control group SWV, control group and CKD1 group (P=0.061), CKD2 group and CKD3 group (P=0.238), CKD4 group and CKD5 group (P=0.624) there was no significant difference between groups (P0.05), is more than 22, SWV value differences were statistically significant (P0.05); SWV values of renal parenchyma and CKD clinical staging was negatively related to the dominant (r=-0.65, P0.001), namely, the higher the stage of CKD, SWV value the more The SWV value is positively correlated with GFR (r=0.73, P0.001), that is, the lower the GFR is, the lower the SWV value. Conclusion VTQ technology can reflect the elastic change of renal parenchyma noninvasively, evaluate the degree of renal function damage in CKD patients, and provide a new quantitative evaluation index for the clinical stages of CKD.

【作者单位】：广东药科大学附属第一医院超声科;广东药科大学附属第一医院肾内科;
【分类号】：R445.1;R692

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