经皮超声造影对乳腺癌腋窝前哨淋巴结良恶性鉴别诊断的价值

发布时间：2018-04-05 14:26

本文选题：前哨淋巴结　切入点：经皮超声造影　出处：《中国超声医学杂志》2015年06期

【摘要】：目的经皮注射超声造影剂微泡对乳腺癌腋窝SLN进行寻找和良恶性的鉴别诊断,旨在探讨经皮下注射超声造影剂判断引流淋巴结的良恶性这一方式的准确度。方法建立兔乳腺癌腋窝淋巴结转移模型,普通超声观察淋巴结,初步判断淋巴结的性质,然后进行经皮超声造影,观察淋巴结超声造影表现,判断其良恶性。结果在灌注情况、开始灌注时间和灌注强度3个指标中,良恶性淋巴结灌注模式具有显著性差异(P=0.001),超声造影诊断恶性淋巴结的准确度明显高于普通二维超声(87.5%vs 50.0%,P0.001)。结论无灌注和灌注缺损是经皮超声造影判断淋巴结良恶性较好的指标,结合二维超声判断淋巴结良恶性准确度明显高于单独使用二维超声。
[Abstract]:Objective to investigate the accuracy of subcutaneous ultrasound contrast agent in the diagnosis of benign and malignant lymph nodes in breast cancer by searching for axillary SLN and differential diagnosis of benign and malignant breast cancer by percutaneous ultrasound contrast agent.Methods the axillary lymph node metastasis model of rabbit breast cancer was established. The lymph nodes were observed by conventional ultrasound, and the nature of lymph nodes was preliminarily determined. Then, percutaneous contrast-enhanced ultrasonography was performed to observe the appearance of lymph nodes and to judge the benign and malignant lymph nodes.Results among the three indexes of perfusion, beginning time and perfusion intensity, there was significant difference between benign and malignant lymph node perfusion patterns. The accuracy of contrast-enhanced ultrasonography in diagnosing malignant lymph nodes was significantly higher than that in normal two-dimensional ultrasonography (87.5 vs 50.0P 0.001).Conclusion Non-perfusion and perfusion defect is a good index for the diagnosis of benign and malignant lymph nodes by percutaneous contrast-enhanced ultrasonography. The accuracy of two-dimensional ultrasonography in the diagnosis of benign and malignant lymph nodes is significantly higher than that in single two-dimensional ultrasound.
【作者单位】：上海交通大学附属第六人民医院超声医学科上海超声医学研究所;
【基金】：上海市自然科学基金项目资助(No.11ZR142700)
【分类号】：R445.1;R737.9

【参考文献】