基于MR图像的原发肿瘤体积测量与鼻咽癌2008分期的相关性研究

发布时间：2018-04-08 17:53

  本文选题：鼻咽癌　切入点：原发肿瘤体积　出处：《南京医科大学学报(自然科学版)》2017年04期

【摘要】：目的:探讨基于MR图像的原发肿瘤体积测量与我国鼻咽癌2008分期中T、N和临床分期的相关性。方法:回顾性分析2011年9月—2015年12月经病理证实的113例鼻咽癌患者的影像学及临床资料。依据我国鼻咽癌2008分期标准判断鼻咽癌患者的T、N和临床分期。基于横断位T2加权压脂像,逐层手动勾画肿瘤边界,采用面积求和法计算肿瘤体积。结果:原发肿瘤体积随T分期进展逐渐增大(P0.01)。相邻T分期间两两比较,T1/T2、T3/T4期间原发肿瘤体积差异有统计学意义(P0.05),T2/T3期间差异无统计学意义(P0.05)。全组颈部淋巴结转移率为83.19%。N0~N3期原发肿瘤体积差异无统计学意义(P0.05)。临床Ⅰ~Ⅳ期原发肿瘤体积差异有统计学意义(P0.01)。相邻临床分期间两两比较,Ⅰ与Ⅱ、Ⅱ与Ⅲ期间差异无统计学意义(P0.05),Ⅲ与Ⅳ期间差异有统计学意义(P0.01)。结论:鼻咽癌原发肿瘤体积与我国2008分期中T和临床分期密切相关,可考虑将鼻咽癌原发肿瘤体积纳入后续分期,以帮助判断疾病预后。
[Abstract]:Objective: to investigate the correlation between the primary tumor volume measurement based on Mr imaging and the clinical staging of nasopharyngeal carcinoma (NPC) in 2008.Methods: the imaging and clinical data of 113 patients with nasopharyngeal carcinoma from September 2011 to December 2015 were retrospectively analyzed.According to the 2008 staging standard of nasopharyngeal carcinoma (NPC) in China, the clinical staging and Ten of nasopharyngeal carcinoma (NPC) patients were evaluated.Based on T 2 weighted fat image in transverse position, the tumor boundary was drawn manually, and the tumor volume was calculated by area summation method.Results: the volume of primary tumor increased with the development of T stage.There was significant difference in primary tumor volume between T 1 / T 2 T 2 T 3 + T 4 and T 2% T 2 / T 3. There was no significant difference in primary tumor volume during T 2 / T 3 and T 2 / T 3. There was no significant difference between T 1 / T 2 and T 2 / T 3.There was no significant difference in cervical lymph node metastasis rate between 83.19%.N0~N3 stage and primary tumor volume (P 0.05).The difference of primary tumor volume in clinical stage 鈪，

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