三维斑点追踪成像评价亚临床甲状腺功能减退患者左心室收缩功能

发布时间：2018-04-15 06:38

本文选题：超声心动描记术 + 心室功能　；参考：《中国医学影像技术》2015年05期

【摘要】：目的评价三维斑点追踪成像(3D-STE)技术对亚临床甲状腺功能减退(SCH)患者左心室心肌功能减低的预测价值。方法对32例SCH患者(SCH组)和30名健康志愿者(对照组)行3D-STE检查,获得左心室收缩期整体面积应变(GAS)、整体纵向应变(GLS)和整体环向应变(GCS)。比较对照组和SCH组治疗前后左心室三维应变参数差异,以左心室射血分数65%为诊断左心室收缩功能减低金标准,采用ROC曲线评价左心室三维应变参数诊断SCH左心室收缩功能减低的效能。结果 SCH组治疗前后GAS、GLS和GCS绝对值均低于对照组(P均0.05),治疗后GAS、GLS和GCS绝对值均高于治疗前(P均0.05)。ROC曲线显示GAS、GLS和GCS的AUC分别为0.805、0.723和0.614,分别以-40.5%、-29.3%和-32.6%作为GAS、GLS和GCS诊断左心室功能减低界值,其敏感度分别为85.7%、77.8%和71.1%,特异度分别为72.2%、71.3%和60.1%。结论 3D-STE中GAS诊断SCH患者左心室收缩功能减低效能较高,具有一定的临床预测价值。
[Abstract]:Objective to evaluate the predictive value of 3 D-STE in subclinical hypothyroidism patients with left ventricular myocardial dysfunction.Methods 3D-STE was performed in 32 patients with SCH and 30 healthy volunteers (control group). The left ventricular systolic total area strain (GASS) and the global circumferential strain (GCS) were obtained.The left ventricular three dimensional strain parameters were compared between the control group and the SCH group before and after treatment. The left ventricular ejection fraction (LVEF) of 65% was used as the gold standard for the diagnosis of left ventricular systolic dysfunction.ROC curve was used to evaluate the effectiveness of left ventricular three-dimensional strain parameters in diagnosing left ventricular systolic dysfunction in SCH.Results the absolute values of GLS and GCS in SCH group were lower than those in control group before and after treatment (P < 0.05). The absolute values of GLS and GCS in SCH group were higher than those in pre-treatment and pre-treatment 0.05).ROC curve. The AUC of GLS and GCS were 0.805 卤0.723 and 0.614, respectively. The GLS and GCS were diagnosed by -40.5-29.3% and -32.6%, respectively.Left ventricular dysfunction threshold,The sensitivity was 77.8% and 71.1%, the specificity was 72.2% and 60.1%, respectively.Conclusion GAS in 3D-STE is more effective in diagnosing left ventricular systolic dysfunction in patients with SCH, and it has certain clinical predictive value.
【作者单位】：同济大学附属东方医院医学超声科;
【基金】：上海市医学重点专科建设计划(ZK2012A27)
【分类号】：R581.2;R540.45

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