速度向量成像技术评价急性心肌缺血左心室扭转运动

发布时间：2018-04-15 12:49

本文选题：速度向量成像 + 急性心肌缺血　；参考：《中国动脉硬化杂志》2015年01期

【摘要】：目的建立新西兰大白兔急性心肌缺血动物模型,应用速度向量成像(VVI)技术分析急性心肌缺血状态下左心室扭转运动的变化特点。方法新西兰大白兔40只,随机分为急性心肌缺血组和假手术组,于冠状动脉结扎术前和术后30 min内行超声心动图检查并采集动态图像,脱机行VVI分析,测量左心室心尖水平及心底水平的旋转角度峰值、旋转速度峰值、解旋速度峰值。结果急性心肌缺血组术后,心底水平左心室旋转角度、旋转速度及解旋速度有减低趋势,但与术前及假手术组比较差异无统计学意义(P0.05);心尖水平左心室旋转角度、旋转速度及解旋速度均明显减低,与术前及假手术组比较差异均有统计学意义(P0.05),左心室整体扭转角度、速度和解旋速度术后改变趋势与心尖水平相似,与术前及假手术组比较差异均有统计学意义(P0.05)。结论急性心肌缺血后,左心室扭转和解旋功能受损,主要由心尖部旋转和解旋减低引起。VVI技术能够客观、准确地检测实验兔左心室扭转的变化特征,为急性心肌缺血的早期诊断提供了一种新的、无创的、可靠的定量工具。
[Abstract]:Objective to establish an animal model of acute myocardial ischemia in New Zealand white rabbits and to analyze the changes of left ventricular torsion motion in acute myocardial ischemia by velocity vector imaging (VVI) technique.Methods 40 New Zealand white rabbits were randomly divided into acute myocardial ischemia group and sham operation group. Echocardiography was performed before and 30 min after coronary artery ligation, and dynamic images were collected. VVI analysis was performed offline.The rotation angle peak, rotation velocity peak and unspin velocity peak of left ventricular apex and heart were measured.Results in the acute myocardial ischemia group, the left ventricular rotation angle, rotation velocity and unrotation velocity were decreased, but there was no significant difference between the two groups before and after operation (P 0.05), and the left ventricular rotation angle at the apex level was similar to that in the sham operation group.The rotation velocity and unrotation velocity were significantly decreased compared with those before operation and sham operation group (P 0.05). The change trend of left ventricular global torsion angle, velocity and rotation velocity after operation was similar to that of the apical level.There was significant difference between preoperation and sham operation group (P 0.05).Conclusion after acute myocardial ischemia, the left ventricular torsion and pronation function are impaired. The technique of .VVI, which is mainly caused by the reduction of rotation and rotation at the apex, can objectively and accurately detect the characteristics of left ventricular torsion in experimental rabbits.It provides a new, non-invasive and reliable quantitative tool for early diagnosis of acute myocardial ischemia.
【作者单位】：中南大学湘雅二医院超声科;南华大学附属第一医院超声科;
【基金】：国家自然科学基金资助(30970838)
【分类号】：R542.2;R445.1

【参考文献】