胼胝体压部可逆性孤立性病变的MRI、~1H-MRS表现及其持续时间与ADC值相关性的初步研究

发布时间：2018-04-18 10:47

本文选题：脑病 + 胼胝体W　；参考：《临床放射学杂志》2017年08期

【摘要】：目的总结胼胝体压部(SCC)可逆性孤立性病变的MRI、~1H-MRS特点,初步研究病灶持续存在时间与表观扩散系数(ADC)值的相关性。方法回顾性分析15例SCC可逆性孤立性病变患者的临床及影像表现,探讨SCC病灶持续时间与年龄、最大横截面积、ADC值的相关关系,以病灶持续时间为因变量(Y),年龄(X_1)、最大横截面积(X_2)、ADC值(X_3)为自变量,进行逐步回归分析,求出多元线性回归模型。结果病灶位于SCC中线区,单发,边界清楚,呈等/长T_1、长T_2信号,T_2-FLAIR及DWI序列呈高信号,ADC图低信号,增强后无强化,平均经过18.4天后消失。MRS均未见明显异常表现。ADC值与病灶持续时间呈中度正相关(r=0.624,P0.05),病灶持续时间的影响因素包括最大横截面积和ADC值(R~2=0.618,F=2.924,P=0.012),多元逐步回归分析结果显示,ADC值对病灶持续时间有正向预测作用(R~2=0.389,F=8.277,P=0.013)。结论 SCC可逆性孤立性病变的MRI表现具有明显的特征性,对其明确诊断具有重要意义,并可根据其ADC值初步推测病灶持续存在的时间。
[Abstract]:Objective to study the correlation between the duration of lesion and the apparent diffusion coefficient (ADCC) in the reversible solitary lesion of corpus callosum (SCC).Methods the clinical and imaging findings of 15 patients with reversible solitary lesion of SCC were retrospectively analyzed, and the correlation between the duration of SCC and age, maximum cross-sectional area and ADC value was investigated.Taking the duration of lesion as dependent variable, age X _ 1 and maximum cross-sectional area X _ 2D / D _ (3) as independent variables, a stepwise regression analysis was carried out and a multivariate linear regression model was obtained.Results the lesion was located in the middle line of SCC, with a single lesion, with a clear boundary, with an equal / long T _ 1, and a long T _ 2 signal with T _ 2-flair and DWI sequences with low signal and low signal, but no enhancement after enhancement.After 18.4 days, there was no obvious abnormal manifestation. ADC value was positively correlated with the duration of lesion. The influencing factors of lesion duration included the maximum cross-sectional area and ADC value. The results of multivariate stepwise regression analysis showed that there was no significant correlation between the value of ADC and the duration of lesion.The ADC value had a positive predictive effect on the duration of lesion.Conclusion the MRI findings of reversible solitary lesions of SCC have obvious characteristics, which is of great significance for the definite diagnosis, and the duration of the lesion persistence can be preliminarily estimated according to its ADC value.
【作者单位】：泰山医学院;千佛山医院影像科;
【分类号】：R445.2;R742

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