分化型甲状腺癌临床及超声特征与颈部淋巴结转移的相关性分析

发布时间：2018-04-20 02:06

本文选题：分化型甲状腺癌 + 临床特征　；参考：《中国超声医学杂志》2017年06期

【摘要】：目的探讨分化型甲状腺癌颈部淋巴结转移的相关因素。方法回顾性分析336例经手术病理证实的分化型甲状腺癌患者的临床及超声资料,将甲状腺原发肿物特征与颈部淋巴结转移情况进行对照研究。结果单因素分析,年龄45岁、男性患者、甲状腺原发肿物多灶性、最大径1cm、肿物形态不规则、肿物侵犯或紧邻甲状腺被膜、肿物血供丰富以及肿物位于背侧的患者颈部淋巴结转移率更高(P0.05)。多因素分析(Logistic回归分析),患者年龄、甲状腺原发肿物侵犯或紧邻甲状腺被膜以及肿物的丰富血流为分化型甲状腺癌颈部淋巴结转移的独立危险因素。按相关程度由大到小排序为:甲状腺原发肿物侵犯或紧邻甲状腺被膜肿物血流丰富年龄(45岁)。结论分化型甲状腺癌颈部淋巴结转移存在一定的高危因素。对于存在高危因素的患者,术前超声检查更需要仔细扫查,寻找颈部有无转移淋巴结征象。
[Abstract]:Objective to investigate the related factors of cervical lymph node metastasis in differentiated thyroid carcinoma. Methods the clinical and ultrasonic data of 336 patients with differentiated thyroid carcinoma confirmed by operation and pathology were analyzed retrospectively. The characteristics of primary thyroid tumor and cervical lymph node metastasis were compared. Results univariate analysis showed that male, aged 45 years, had multiple thyroid masses with a maximum diameter of 1 cm. The tumor was irregular in shape, invading or adjacent to the thyroid capsule. The cervical lymph node metastasis rate was higher in patients with abundant blood supply and dorsal tumor. Multivariate logistic regression analysis showed that age, thyroid primary tumor invasion or adjacent thyroid capsule, and abundant blood flow were independent risk factors for cervical lymph node metastasis of differentiated thyroid carcinoma. According to the degree of correlation from large to small, the age of the thyroid primary tumor invading or adjacent to the thyroid capsule tumor is rich blood flow, and the age is 45 years old. Conclusion there are some risk factors for cervical lymph node metastasis in differentiated thyroid carcinoma. For patients with high-risk factors, preoperative ultrasonography is more necessary to search for metastatic lymph node signs in the neck.
【作者单位】：北京大学第三医院超声诊断科;河北省直属机关第二门诊部超声科;
【分类号】：R445.1;R736.1

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