经阴道三维能量多普勒超声评估早孕期绒毛滋养动脉以预测先兆流产结局的临床研究

发布时间：2018-04-22 07:25

本文选题：经阴道 + 三维能量多普勒超声　；参考：《现代妇产科进展》2016年08期

【摘要】：目的:探索三维能量多普勒超声(3D-CPA)测定早孕期绒毛间隙循环血流变化预测先兆流产结局的临床应用价值。方法:随机选取孕6~8周先兆流产患者62例,将患者按保胎结局分为继续妊娠组、完全流产组。同期选取宫内正常早孕32例作为对照组。行经阴道彩色多普勒超声检测绒毛膜滋养动脉血流的PS、ED、S/D、RI值,以及相关三维超声血流参数(VI、FI、VFI),比较各组差异。结果:与对照组比较,继续妊娠组的绒毛膜滋养动脉ED上升,S/D、RI均下降;完全流产组的ED下降,S/D、RI均上升,差异均有统计学意义(P0.05)。与继续妊娠组比较,完全流产组的ED显著降低,S/D、RI均上升(P0.05)。继续妊娠组和完全流产组的三维参数VI、VFI均高于对照组,完全流产组较继续妊娠组增高明显,差异有统计学意义(P0.05)。3组的PS、FI值比较,差异均无统计学意义(P0.05)。结论:利用阴道3D-CPA探测孕6~8周先兆流产患者的绒毛间隙血流相关参数(ED、S/D、RI、VI、VFI),可以为综合预测先兆流产结局提供有价值的参考信息。
[Abstract]:Objective: to explore the clinical application value of three dimensional energy Doppler ultrasound 3D-CPA in predicting the outcome of threatened abortion. Methods: 62 patients with threatened abortion at 6 weeks and 8 weeks of gestation were randomly selected and divided into continuous pregnancy group and complete abortion group according to the outcome of fetal preservation. 32 cases of normal intrauterine early pregnancy were selected as control group. The PSV EDV / DV RI values of choriotrophoblastic artery blood flow were measured by transvaginal color Doppler ultrasound, and the relevant parameters of three dimensional ultrasound flow were compared. Results: compared with the control group, the Ed of the choriotrophoblastic artery in the continued pregnancy group increased and the Ed / DNRI decreased in the group of complete abortion, and the difference was statistically significant (P 0.05). Ed in the complete abortion group was significantly lower than that in the continuous pregnancy group. The VII-VFI of the continuous pregnancy group and the complete abortion group were higher than that of the control group. The total abortion group was significantly higher than that of the continuous pregnancy group, and the difference was statistically significant (P 0.05). There was no significant difference between the two groups. Conclusion: using vaginal 3D-CPA to detect the relevant parameters of chorionic space blood flow in patients with threatened abortion at the 6th week and 8th week of gestation can provide valuable reference information for comprehensive prediction of the outcome of threatened abortion.
【作者单位】：三峡大学医学院;宜昌市中心人民医院超声科;三峡大学仁和医院超声科;
【分类号】：R714.21;R445.1

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