伴认知功能障碍的颞叶癫痫MRI研究进展

发布时间：2018-04-22 16:48

本文选题：颞叶 + 癫痫　；参考：《中国医学影像技术》2017年09期

【摘要】：颞叶癫痫(TLE)是癫痫最常见的类型,其反复发作可致患者记忆力、语言及执行力等认知功能损害,使患者生存质量进一步下降。但颞叶癫痫导致认知功能障碍的机制尚不清楚,无法进行相关治疗。随着MR和图像后处理技术的发展,采用DTI、基于体素的形态学分析(VBM)和fMRI技术研究颞叶癫痫伴认知障碍患者脑结构和脑网络变化,发现认知障碍与部分脑区的结构和功能改变具有相关性。本文对伴认知障碍的TLE患者脑结构和功能改变的研究进展进行综述。
[Abstract]:Temporal lobe epilepsy (TLEs) is the most common type of epilepsy. Repeated seizures may lead to cognitive impairment such as memory, language and executive ability, and further decrease the quality of life of patients. However, the mechanism of cognitive impairment caused by temporal lobe epilepsy is not clear and can not be treated. With the development of Mr and image post-processing techniques, the changes of brain structure and brain network in patients with temporal lobe epilepsy with cognitive impairment were studied by using DTI, VBM-based morphologic analysis and fMRI techniques. It was found that cognitive impairment was correlated with structural and functional changes in some brain regions. This article reviews the changes of brain structure and function in TLE patients with cognitive impairment.
【作者单位】：首都医科大学宣武医院放射科;
【基金】：北京市医院管理局临床医学发展专项经费(ZYLX201609)
【分类号】：R445.2;R742.1

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