磁共振扩散峰度成像在颅内星形细胞肿瘤术前评估中的应用

发布时间：2018-04-25 20:47

本文选题：扩散峰度成像 + 星形细胞肿瘤　；参考：《实用医学杂志》2015年18期

【摘要】：目的:研究磁共振扩散峰度成像(DKI)在星形细胞肿瘤术前评估中的应用价值。方法:收集经手术病理证实的星形细胞肿瘤患者25例,其中低级别肿瘤11例,高级别肿瘤14例,均进行常规MRI及DKI检查,测量肿瘤实质区及对侧正常脑白质区的MK及FA值。应用白质纤维束成像技术显示肿瘤周围的脑白质纤维束。结果:MK及FA值均随肿瘤级别增高而增高,且均具有统计学意义(P0.05)。白质纤维束成像显示:低级别肿瘤周围白质纤维束以受压移位为主。高级别肿瘤周围白质纤维束以受浸润及破坏为主。结论:磁共振扩散峰度成像获得的星形细胞肿瘤实质区的MK及FA值有助于肿瘤级别的判定,联合应用白质纤维束成像技术可对患者更好的进行术前评估,优化治疗方案。
[Abstract]:Objective: to study the value of Mr diffusion kurtosis imaging (DKI) in preoperative evaluation of astrocytic tumors. Methods: Twenty-five cases of astrocytoma proved by operation and pathology were collected, including 11 cases of low grade tumors and 14 cases of high grade tumors. Routine MRI and DKI examinations were performed to measure the MK and FA values in the parenchymal and contralateral white matter areas of the brain. The white matter bundle imaging technique was used to display the white matter bundle around the tumor. Results the ratio of MK and FA increased with the increase of tumor grade, and both had statistical significance (P 0.05). White matter fiber bundle imaging showed that the white matter bundle around low grade tumor was mainly displaced by compression. The white matter bundles around high grade tumors were mainly infiltrated and destroyed. Conclusion: the MK and FA values of astrocytoma parenchyma obtained by diffusion kurtosis imaging are helpful in judging the grade of astrocytoma. The combination of white matter fiber bundle imaging can better evaluate the patients before operation and optimize the treatment plan.
【作者单位】：滨州医学院附属医院放射科;
【基金】：山东省自然科学基金资助项目(编号:ZR2011HL038)
【分类号】：R739.4;R445.2

【参考文献】