磁共振弥散张量示踪用于颈椎管内肿瘤的形态学研究

发布时间：2018-05-03 21:31

本文选题：磁共振成像 + 弥散张量成像　；参考：《第二军医大学学报》2015年11期

【摘要】：目的探讨颈椎管内肿瘤患者颈髓弥散张量纤维束示踪(DTT)的影像特点及其与脊髓功能、预后的关系。方法选取2014年2月至2015年1月在南京军区福州总医院经手术切除的颈椎管内肿瘤24例,在术前3d及术后1个月行颈髓弥散张量成像(DTI)扫描,并通过DTT重建白质纤维束,观察纤维束走行及完整性情况。采用McCormick分级法进行脊髓功能的评估。结果 DTT可清晰显现纤维束的饱满或稀疏情况、完整或中断现象,也可以观察纤维束与肿瘤之间的空间位置关系,如纤维束是受肿瘤推压移位还是包绕肿瘤。术前纤维束形态与McCormick分级及预后有关系,纤维束形态完整的患者术前脊髓功能状态及术后1个月时的预后均优于中断型(P0.05)。结论 DTT能直观显示白质纤维束的形态,并对颈椎管内肿瘤的预后判断具有参考价值。
[Abstract]:Objective to investigate the imaging features of diffuse Zhang Liang tracer of cervical spinal cord (DTT) and its relationship with spinal cord function and prognosis in patients with cervical spinal canal tumor. Methods from February 2014 to January 2015, 24 cases of cervical spinal cord tumors were surgically resected in Fuzhou General Hospital of Nanjing military region. The cervical spinal cord diffusive Zhang Liang imaging was performed 3 days before operation and 1 month after operation, and the white matter fiber bundle was reconstructed by DTT. Observe the path and integrity of the fiber bundle. Spinal cord function was evaluated by McCormick classification. Results DTT could clearly show the fullness or sparsity of the fibrous bundles, complete or interrupted, and observe the spatial relationship between the fibrous bundles and the tumor, such as whether the fibrous bundles were displaced by the tumor or wrapped around the tumor. The morphology of the fibrous bundle was correlated with the McCormick grade and prognosis. The preoperative spinal cord function and the prognosis at one month after operation in the patients with intact fibrous bundle were better than those in the interrupted group (P 0.05). Conclusion DTT can visualize the morphology of white matter fiber bundle and has reference value in predicting the prognosis of cervical spinal tumor.
【作者单位】：第二军医大学福州临床医学院(南京军区福州总医院)神经外科;
【分类号】：R445.2;R739.91

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