四维自动左室定量分析技术评估青年肥胖型高血压患者左心室收缩功能的临床研究

发布时间：2018-05-06 10:09

本文选题：四维自动左室定量分析技术 + 青年肥胖　；参考：《广西中医药大学》2017年硕士论文

【摘要】：目的:应用四维自动左室定量分析技术(4-Dimensional auto left ventricular quantification,4D-LVQ)对青年肥胖型高血压患者定量分析左心室收缩功能,探讨4D-LVQ对评估青年肥胖型高血压患者左心室收缩功能改变的应用价值。方法:选取青年肥胖型高血压患者组30例,青年高血压患者组30例,正常青年组30例,共90例,三组实验组。采集经胸标准清晰的心尖四腔心切面得四维全容积图像数据并存储,并应用4D-LVQ软件在线分析左心室不同水平及整体轴向收缩峰值应变(longtiudinal peak strain,LS)、环向收缩峰值应变(circumferential peak strain,CS)、径向收缩峰值应变(radial peak strain,RS)及面积收缩峰值应变(area peak strain,AS)的牛眼图,并对比这三组人群的应变情况。结果:1.与正常青年组比较,青年高血压患者组RS值中乳头肌水平、心尖水平、心尖部及整体水平升高(p0.05)。其余节段水平不同应变值两组比较差异无统计学意义。2.与正常青年组比较,青年肥胖型高血压患者组LS值中二尖瓣水平、乳头肌水平及整体水平降低(p0.05);CS值中二尖瓣水平、心尖部及整体水平降低(p0.05);RS值中二尖瓣水平、乳头肌水平、心尖水平、心尖部及整体水平降低(p0.05);AS值中二尖瓣水平、乳头肌水平、心尖部及整体水平降低(p0.05)。其余节段水平不同应变值两组比较差异无统计学意义。3.与青年高血压患者组比较,青年肥胖型高血压患者组LS值中二尖瓣水平、乳头肌水平、心尖水平及整体水平降低(p0.05);CS值中二尖瓣水平、心尖水平、心尖部及整体水平降低(p0.05);RS值中二尖瓣水平、乳头肌水平、心尖部及整体水平降低(p0.05);AS值中二尖瓣水平、心尖部及整体水平降低(p0.05)。其余节段水平不同应变值两组比较差异无统计学意义。结论:青年肥胖型高血压组患者早期LVEF处于正常范围时已出现左心室收缩功能降低。4D-LVQ技术能客观、定量、全面地评估左心室整体及局部心肌功能,可作为临床评价早期心功能异常的参考指标。
[Abstract]:Objective: to evaluate the value of 4-dimensional auto left ventricular quantification4D-LVQ in evaluating the left ventricular systolic function in young obese hypertensive patients by using four-dimensional automatic left ventricular quantitative analysis (4-dimensional auto left ventricular quantification4D-LVQs), and to evaluate the value of 4D-LVQ in evaluating the changes of left ventricular systolic function in young obese hypertensive patients. Methods: thirty young obese hypertension patients, 30 young hypertension patients and 30 normal young people were selected. The four-dimensional full-volume image data were collected and stored from the standard quadrilateral section of the heart through the chest. 4D-LVQ software was used to analyze the longitudinal peak strain of left ventricle at different levels and the whole axial contraction peak strain, circumferential peak strain, radial peak strain and area peak contraction strain area peak strainas. The response of the three groups was compared. The result is 1: 1. Compared with the normal young group, the levels of papillary muscle, apical, apical and whole heart were increased in the young hypertensive group (P 0.05). There was no significant difference between the two groups in the level of other segments, different strain values. 2. 2. Compared with the normal young group, the mitral valve level, the papillary muscle level and the whole level of mitral valve, mitral valve and papillary muscle were decreased in the young obese hypertension group, and the mitral valve level and the papillary muscle level were decreased in the apical region and the whole heart, and the middle mitral valve level and the papillary muscle level in the middle mitral valve value and the papillary muscle value were decreased in the apical part and the whole heart. The level of mitral valve, the level of papillary muscle, the apical part and the whole level of mitral valve, papillary muscle, apical part and whole were decreased by p0.05. There was no significant difference between the two groups in the level of other segments, different strain values. 3. 3. Compared with the young patients with hypertension, the mitral valve level, papillary muscle level, apical level and the whole level of mitral valve, mitral valve and apical value in the young obese hypertension group were significantly lower than those in the young hypertension group, and the mitral valve level and the apical value in the CS value were significantly lower than those in the control group. The level of mitral valve, the level of papillary muscle, the level of apical part and the whole level of mitral valve were decreased in the apical part and the whole level, the level of mitral valve in the apical part and the whole level was decreased (p 0.05), and the level of the apical part and the whole body was decreased (P 0.05). There was no significant difference between the two groups at other levels. Conclusion: in the young obese hypertension group, the left ventricular systolic function has been decreased in the early stage of LVEF. 4D-LVQ can be used to evaluate the global and local myocardial function of the left ventricle objectively, quantitatively and comprehensively. It can be used as a reference index for clinical evaluation of early cardiac dysfunction.
【学位授予单位】：广西中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R544.1;R540.45

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