弥散张量成像鉴别诊断肾透明细胞癌与肾盂移行细胞癌

发布时间：2018-05-06 22:20

  本文选题：癌 + 肾细胞　； 参考：《中国介入影像与治疗学》2017年05期

【摘要】：目的评价MRI弥散张量成像(DTI)在肾透明细胞癌(ccRCC)与肾盂移行细胞癌(TCC)鉴别诊断中的价值。方法回顾性分析行腹部MR检查、经病理证实为ccRCC及TCC的患者38例(ccRCC 29例,TCC 9例)。患者均行MR T1W脂肪抑制和T2W脂肪抑制序列扫描、LAVA增强扫描、DTI序列扫描(b=0、600s/mm~2)。由2名放射科医师采用AW 4.4工作站采用Functool后处理软件进行图像分析和测量。采用组内相关系数(ICC)检验2名察者所测数据的一致性。ccRCC和TCC ADC值及FA值的比较采用独立样本t检验。采用ROC曲线分析ADC值、FA值对ccRCC与TCC的鉴别诊断效能。结果 2名观察者测量各参数一致性良好(ICC值均0.75)。ccRCC的ADC值[(2.03±0.49)×10~(-3) mm~2/s]高于TCC[(1.57±0.43)×10~(-3 )mm~2/s;P=0.015)],但ccRCC的FA值(0.24±0.10)低于TCC(0.42±0.22);P=0.002)。ADC值曲线下面积0.761(P0.05),敏感度和特异度分别为79.3%、77.8%,阈值为1.59×10~(-3) mm~2/s。FA值曲线下面积为0.762(P0.05),敏感度和特异度分别为66.7%、93.1%,阈值为0.326。结论 MR DTI可有效鉴别ccRCC和肾盂TCC,其中FA值对鉴别两者的特异度较高。
[Abstract]:Objective to evaluate the value of MRI diffusion Zhang Liang imaging in differential diagnosis of renal clear cell carcinoma (RCC) and transitional cell carcinoma of renal pelvis (TCC). Methods the abdominal Mr examination was performed retrospectively in 38 patients with ccRCC and TCC confirmed by pathology. There were 29 patients with ccRCC and 9 patients with TCCs. Mr T1W fat suppression and T2W fat suppression sequences were performed in all patients. Two radiologists used AW 4.4 workstation to carry out image analysis and measurement with Functool post processing software. The consistency of the data measured by the two subjects was compared with the values of TCC ADC and FA. The independent sample t test was used to test the consistency of the data. ROC curve was used to analyze the effectiveness of ADC value and FA value in differential diagnosis of ccRCC and TCC. 缁撴灉 2鍚嶈�傚療瑁�

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