脊柱外周原始神经外胚层瘤CT、MRI及病理表现

发布时间：2018-05-07 01:29

本文选题：原始神经外胚层瘤 + X线计算机　；参考：《中国医学计算机成像杂志》2015年02期

【摘要】：目的:分析脊柱外周原始神经外胚层瘤(p PNET)的CT、MRI及病理表现,提高对本病的认识。方法:回顾性分析13例经手术病理证实的p PNET。结果:单发病灶10例,多发病灶3例。11例伴有椎体、附件骨质破坏。8例累及椎管内外,1例脊髓受侵,5例患者可见不典型哑铃征,4例伴有转移。CT平扫为等或低密度,MR平扫T1WI为等或低信号,T2WI为高或混杂高信号;增强扫描明显不均匀强化。病理上光镜下以小圆细胞及HomerWright玫瑰结为特征,免疫组化有两项以上神经源性抗体表达阳性,以CD99为著。结论:p PNET无明显特异性影像学表现,诊断主要靠病理和免疫组化。CT、MRI可以清楚的显示病灶的范围、内部结构及肿块与周围组织的关系,对手术方案的制定具有重要的临床意义。
[Abstract]:Objective: to analyze the CT MRI and pathological features of peripheral primitive neuroectodermal tumor (PNET) of spinal column, and to improve the understanding of this disease. Methods: 13 cases of p PNET proved by operation and pathology were analyzed retrospectively. Results: there were 10 cases with single focus, 3 cases with multiple lesions and 11 cases with vertebral body. In 8 cases of adnexal bone destruction, 1 case was involved in spinal canal and 1 case by spinal cord invasion. 4 cases of atypical dumbbell sign were found with metastasis. Ct plain scan was iso-or low-density Mr plain scan, T1WI was equal or low signal intensity and T _ 2WI was hyperintense or mixed. The enhancement scan was obviously uneven enhancement. Pathological light microscopy was characterized by small round cells and HomerWright rose-knot. More than two neurogenic antibodies were positive in immunohistochemical staining, especially CD99. Conclusion there is no specific imaging manifestation in the PNET. The diagnosis mainly depends on pathology and immunohistochemistry. CTT MRI can clearly show the extent of lesion, internal structure and the relationship between mass and surrounding tissue, which is of great clinical significance for the establishment of surgical plan.
【作者单位】：第二军医大学附属上海长征医院影像诊断科;中国人民解放军第413医院放射科;
【分类号】：R738.1;R730.44;R445.2

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