高血压患者主动脉重构与左心房重构的超声研究附924例分析

发布时间：2018-05-13 03:10

本文选题：高血压 + 主动脉　；参考：《新疆医科大学》2014年硕士论文

【摘要】：目的：探讨原发性高血压患者与主动脉重构和左房重构相关的诸因素变化特点及相互关系。方法：随机抽查在新疆医科大学第一附属医院诊断为原发性高血压的924例住院患者,根据主动脉及左房是否重构扩大分为主动脉增宽左房增大组、主动脉增宽左房正常组、左房增大主动脉正常组、主动脉正常左房正常组,分别测量各组患者的左房收缩末期内径(LADs)、主动脉窦部内径、左心室舒张末期内径(LVEDd),舒张期室间隔及左室后壁厚度(IVSd、LVPWd)并计算左心室质量指数(LVMI)心脏指标。另外,测定924例住院患者的年龄、性别,体重指数(BMI),收缩压,舒张压,病程及治疗时间等其他指标；运用t检验,卡方检验分析上述指标的差异,用logistics回归方法分析上述因素对主动脉重构和左心房重构的影响,并做ROC曲线计算引起主动脉重构和左心房重构最重要的指标。结果：1.主动脉与左房均重构组的年龄、BMI、LVMI、收缩压、舒张压、病程均高于两者未重构组,LVMI、收缩压、舒张压均高于主动脉增宽左房正常组(P0.05)。2.主动脉增宽左房正常组的年龄、LVMI、收缩压、病程高于主动脉正常左房正常组(P0.05),其年龄高于主动脉正常左房增大组,治疗时间短于主动脉正常左房正常组。3.主动脉正常左房增大组的年龄、BMI、LVMI、舒张压均高于主动脉正常左房正常组,治疗时间短于主动脉正常左房正常组。结论：年龄是引起主动脉重构的重要影响因素,而LVMI是引起左心房重构的重要影响因素。
[Abstract]:Objective: To investigate the characteristics and relationship of various factors associated with aortic remodeling and left atrial remodeling in patients with essential hypertension. Methods: 924 hospitalized patients diagnosed as primary hypertension at the First Affiliated Hospital of Xinjiang Medical University were randomly selected to be divided into aorta and left atrium by enlargement of aorta and left atrium to the widening of the left atrium. In the large group, the aorta widened the left atrial normal group, the left atrial enlargement of the normal group, the normal left atrium of the aorta, the left atrial end systolic diameter (LADs), the internal diameter of the aortic sinus, the left ventricular end diastolic diameter (LVEDd), the diastolic interventricular septum and the left ventricular posterior wall thickness (IVSd, LVPWd), and the left ventricular mass index (LV). MI) cardiac index. In addition, the age, sex, body mass index (BMI), systolic pressure, diastolic pressure, course of disease and treatment time were measured in 924 hospitalized patients. The differences of the above indexes were analyzed by t test and chi square test. The effects of these factors on the remodeling of aorta and left atrium were analyzed with the logistics regression method, and the ROC curve was made. Results: 1. the age, BMI, LVMI, systolic pressure, diastolic pressure, and diastolic pressure of both aorta and left atrial remodeling group were higher than those in the two groups, LVMI, systolic pressure and diastolic pressure were higher than that of the aorta widened left atrial normal group (P0.05),.2. aorta widened the normal group of left atrium, LVMI. The course of contraction is higher than that of normal left atrium of aorta (P0.05). The age is higher than that of normal left atrium. The treatment time is shorter than that of normal left atrium of the aorta, normal left atrial enlargement group of.3. aorta, BMI, LVMI, and the diastolic pressure is higher than that of normal left atrium of aorta, and the time of treatment is shorter than normal left atrium of aorta. Conclusion: age is an important factor affecting aortic remodeling, and LVMI is an important factor affecting left atrial remodeling.

【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R445.1

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