超声二维应变成像技术评价高血压患者的颈动脉弹性

发布时间：2018-05-13 15:08

  本文选题：颈动脉弹性 + 高血压　； 参考：《中华高血压杂志》2015年12期

【摘要】：目的应用超声二维应变成像技术评价高血压患者的颈动脉血管弹性。方法选取2012年1月至12月在天津医科大学第二医院心内科住院的高血压患者120例(1、2和3级高血压组)和正常血压及正常高值血压者40人(对照组)。所有入选对象均行心脏超声检查及颈动脉彩色多普勒超声心动图(彩超)检查,应用二维应变成像技术测量颈动脉短轴方向收缩期峰值整体圆周应变、收缩早期整体圆周应变率(CSr)、收缩晚期整体CSr绝对值,计算僵硬系数(β1和β2)。结果随着血压升高,室间隔厚度(IVST)[(8.2±1.4)、(9.1±1.1)、(9.4±1.4)、(11.2±2.2)mm]、左心室后壁厚度(LVPWT)[(8.5±1.1)、(8.6±1.0)、(9.2±1.4)、(10.7±2.2)mm]、左心室质量指数(LVMI)[(53.3±10.8)、(59.6±15.8)、(60.2±10.1)、(76.4±26.2)g/m2]、β2[(0.6±0.1)、(0.8±0.2)、(0.9±0.2)、(1.1±0.2)]逐渐升高;而收缩期峰值整体圆周应变[(6.0±0.7)%、(5.4±0.1)%、(5.0±0.3)%、(4.7±0.4)%]、收缩早期整体CSr(×10)[(7.1±0.8)/s、(6.3±0.6)/s、(5.5±0.5)/s、(5.1±0.5)/s]降低(均P0.05)。相关性分析显示,LVMI与收缩期峰值整体圆周应变、收缩早期整体CSr和收缩晚期整体CSr绝对值呈负相关;与β2呈正相关。结论高血压患者收缩期整体圆周应变、收缩早期整体CSr随血压水平增高而减小,β2随着血压水平的增高增大,提示随着血压增高颈动脉僵硬度增加,超声二维应变成像技术可作为一项诊断血管弹性病变的新技术。
[Abstract]:Objective to evaluate carotid artery elasticity in patients with hypertension by two-dimensional strain imaging. Methods from January to December, 2012, 120 patients with hypertension in Department of Cardiology, second Hospital of Tianjin Medical University, and 40 patients with normal blood pressure and normal high blood pressure (control group) were selected. All subjects were examined by echocardiography and color Doppler echocardiography (CDFI) of carotid artery. Two-dimensional strain imaging technique was used to measure the global circumferential strain of peak systolic peak in short axis of carotid artery. The stiffness coefficients (尾 _ 1 and 尾 _ 2) were calculated by the whole circumferential strain rate (CSR) in the early stage of contraction and the absolute value of global CSr in the late stage of contraction. 缁撴灉闅忕潃琛，

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