体素内不相干运动扩散加权成像在乳腺病变中的初步应用

发布时间：2018-05-16 15:53

本文选题：IVIM-DWI + 乳腺　；参考：《福建医科大学学报》2015年04期

【摘要】：目的初步探讨体素内不相干运动扩散加权成像(IVIM-DWI)在乳腺良、恶性病变鉴别诊断中的应用。方法测量60例行1.5T磁共振扫描的乳腺疾病患者病变的IVIM参数:标准扩散系数(Standard ADC)、真实扩散系数(Slow ADC)、灌注相关扩散系数(Fast ADC)及灌注系数f(Fraction)值。根据病理结果将患者分为良、恶性病变组,并取其自身对侧正常的乳腺组织为对照组,对3组的定量参数进行统计学分析。比较3组的组内Standard ADC、Slow ADC值的差别,分析其ROC曲线。结果对照组、良性病变与恶性病变组的Standard ADC、Slow ADC值依次降低,且两两比较差别有统计学意义(P0.01);对照组、良性病变与恶性病变组的Fast ADC、Fraction值依次升高,进一步两两比较,Fraction值的差别有统计学意义(P0.01),Fast ADC值仅对照组与良性病变组间的差别有统计学意义(P0.01)。3组组内Standard ADC和Slow ADC值的差别有统计学意义(P0.01),Slow ADC的ROC曲线下面积大于Standard ADC。结论 IVIM-DWI对乳腺良恶性病变的鉴别诊断有意义,可提高诊断的敏感性。
[Abstract]:Objective to investigate the application of incoherent motion diffusion-weighted imaging (IVIM-DWI) in the differential diagnosis of benign and malignant breast lesions. Methods to measure the IVIM parameters of 60 cases of breast disease with 1.5T MRI scan: standard diffusion coefficient (Standard ADC), true diffusion coefficient (Slow ADC), perfusion related diffusion coefficient (Fast ADC) and The perfusion coefficient f (Fraction) value. According to the pathological results, the patients were divided into benign and malignant lesions, and their contralateral normal breast tissue was taken as the control group. The quantitative parameters of the 3 groups were statistically analyzed. The differences in the Standard ADC and Slow ADC values in the 3 groups were compared, and the ROC curves were analyzed. The result control group, the benign lesion and the malignant lesion group, was analyzed. The value of Standard ADC and Slow ADC decreased in turn, and the difference between 22 was statistically significant (P0.01). In the control group, the value of Fast ADC and Fraction in the benign and malignant lesions increased in turn, and the difference of Fraction values was statistically significant (P0.01), and Fast ADC was statistically significant between the control group and the benign lesion group. The difference between Standard ADC and Slow ADC in group P0.01.3 group was statistically significant (P0.01). The area under ROC curve of Slow ADC was greater than that of Standard ADC. conclusion, which was significant for the differential diagnosis of benign and malignant breast lesions, and could improve the sensitivity of the diagnosis.

【作者单位】：福建省肿瘤医院放诊科;
【分类号】：R737.9;R445.2

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