超声弹性应变率比值联合磁共振成像对乳腺肿物的诊断

发布时间：2018-05-18 14:06

本文选题：乳腺肿瘤 + 超声检查　；参考：《中国医学影像学杂志》2015年12期

【摘要】：目的评价超声弹性应变率比值与MRI及其联合应用对乳腺肿物的诊断价值。资料与方法收集经手术病理证实为乳腺良恶性肿物的54例患者,均行弹性超声及MRI检查,通过定量超声弹性成像技术测定肿物与周围正常乳腺组织的应变率比值(SRR),绘制受试者操作特征(ROC)曲线获得区分乳腺肿物良恶性的最佳临界值,比较超声SRR、MRI及两者联合应用诊断乳腺肿物的准确度。结果良性组SRR为2.24±1.28,与恶性组的4.96±1.73比较,差异有统计学意义(t=2.648,P0.05)。通过ROC曲线确定超声SRR诊断乳腺肿物良恶性的最佳临界值为2.41。超声SRR、MRI、SRR联合MRI应用诊断乳腺良恶性肿物的准确度分别为81.48%(44/54)、85.19%(46/54)、96.30%(52/54);超声SRR与MRI诊断准确度比较,差异无统计学意义(χ~2=0.267,P0.05);联合诊断准确度明显高于超声SRR、MRI的诊断准确度(χ~2=6.000、3.967,P0.05)。结论超声SRR对乳腺肿瘤良恶性的诊断准确性较高,可为临床鉴别诊断乳腺实性病灶良恶性提供更有价值的量化指标,同时结合MRI诊断可减少误诊和漏诊。
[Abstract]:Objective to evaluate the diagnostic value of ultrasound elastic strain rate ratio (ESR) combined with MRI in the diagnosis of breast masses. Materials and methods 54 patients with benign and malignant breast masses confirmed by surgery and pathology were examined by elastic ultrasound and MRI. The strain rate ratio of the tumor to the surrounding normal mammary gland was measured by quantitative ultrasound elastography, and the optimum critical value for differentiating benign and malignant breast masses was obtained by drawing the ROC curve of the subjects. To compare the accuracy of SRR MRI and its combination in the diagnosis of breast masses. Results the SRR of benign group was 2.24 卤1.28, which was significantly higher than that of malignant group (4.96 卤1.73). The best critical value for the diagnosis of benign and malignant breast masses by SRR was determined to be 2.41 by ROC curve. The accuracy of diagnosis of benign and malignant breast neoplasms was 81.48%, respectively, in the diagnosis of benign and malignant breast masses by MRI. The diagnostic accuracy of ultrasound SRR was significantly higher than that of MRI (蠂 ~ 20.267P 0.05N) (蠂 ~ 2 / 0.267P 0.05N), and the accuracy of diagnosis of benign and malignant breast neoplasms was 81.48 / 54 / 85.19 / 46 / 54 respectively, and there was no significant difference between the diagnostic accuracy of ultrasound SRR and that of MRI (蠂 ~ 2 / 0.267P0.05N) (蠂 ~ (2 / 0) 6.000 ~ 3.967P0.05). Conclusion Ultrasound SRR has a high accuracy in the diagnosis of benign and malignant breast tumors, which can provide a more valuable quantitative index for clinical differential diagnosis of benign and malignant breast solid lesions. Combined with MRI diagnosis, misdiagnosis and missed diagnosis can be reduced.
【作者单位】：广西医科大学附属肿瘤医院B超室;广西医科大学附属肿瘤医院乳腺外科;广西医科大学肿瘤医学院;广西医科大学附属肿瘤医院放射科;
【基金】：广西卫生厅重点资助课题(重2012088)
【分类号】：R445.1;R445.2;R737.9

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