高频超声诊断早期类风湿关节炎的应用研究

发布时间：2018-05-22 13:19

本文选题：关节炎 + 类风湿　；参考：《重庆医学》2015年18期

【摘要】：目的分析高频超声诊断早期类风湿关节炎的应用价值。方法以该院收治的40例早期类风湿关节炎(RA)患者为观察组,另选择40例健康者作为对照组,分别采用高频超声和X线对两组对象进行影像学检查。对比分析两组的超声检查结果和高频超声与X线对观察组患者膝关节髌上囊积液、滑膜增生及骨侵蚀的阳性检出率,以及观察组患者的C-反应蛋白(CRP)、红细胞沉降率(ESR)指标与超声检查相关指标的相关性。结果观察组患者膝关节髌上囊积液、滑膜增生、滑膜彩色血流、骨侵蚀高频超声检查的阳性率均高于对照组(P0.05);观察组患者的动脉阻力指数小于对照组,股骨内髁及外髁软骨厚度较对照组薄(P0.05)。高频超声对观察组患者膝关节髌上囊积液、滑膜增生、骨侵蚀的阳性检出率均高于X线等检查结果(P0.05)。观察组患者膝关节髌上囊积液厚度、滑膜增生厚度、滑膜彩色血流分级与CRP、ESR均存在一定的相关性(P0.01)。结论高频超声能较好地反映早期RA患者的病变情况,且对各病变的检出率高于X线片,高频超声检查指标与CRP、ESR有一定的相关性。
[Abstract]:Objective to analyze the value of high-frequency ultrasound in the diagnosis of early rheumatoid arthritis. Methods 40 patients with early rheumatoid arthritis (RA) were treated in our hospital as the observation group and 40 healthy persons as the control group. The two groups were examined by high-frequency ultrasound and X-ray respectively. The results of ultrasonic examination and the positive detection rate of suprapatellar sac fluid, synovial hyperplasia and bone erosion in the observation group were compared and analyzed. The correlation between the indexes of C-reactive protein (CRP) and erythrocyte sedimentation rate (ESRR) and ultrasonic examination was also discussed. Results the positive rates of suprapatellar sac effusion, synovial hyperplasia, synovial color flow and bone erosion in the observation group were higher than those in the control group (P 0.05), and the arterial resistance index in the observation group was lower than that in the control group. The thickness of femoral medial condyle and lateral condylar cartilage was thinner than that of control group (P 0.05). The positive rate of superpatellar sac effusion, synovial hyperplasia and bone erosion in the observation group was higher than that in the X-ray examination group (P 0.05). In the observation group, the thickness of suprapatellar sac, synovial hyperplasia, color flow grade of synovium and ESR of CRP were all correlated with P0.01. Conclusion High-frequency ultrasound can better reflect the pathological changes of early RA patients, and the detection rate of each lesion is higher than that of X-ray film. The index of high-frequency ultrasound is correlated with the ESR of CRPU.
【作者单位】：广东省佛山市顺德区第一人民医院血液风湿科;
【基金】：佛山市医学类科技攻关项目(201208209)
【分类号】：R445.1;R593.22

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