甲状腺未分化癌和乳头状癌超声成像特征的差异

发布时间：2018-05-28 02:30

本文选题：甲状腺未分化癌 + 甲状腺乳头状癌　；参考：《中国医学科学院学报》2015年01期

【摘要】：目的探讨甲状腺未分化癌和甲状腺乳头状癌超声成像特征的差异。方法回顾性分析2001年4月至2014年6月在北京协和医院就诊并经病理证实的7例甲状腺未分化癌的临床和超声特征,并以同时期内性别、年龄相匹配的21例经病理证实甲状腺乳头状癌患者为对照,分析两组的超声特征差异。结果甲状腺未分化癌的患者以女性为主(5/7,71.4%),平均发病年龄为(64.9±11.3)岁。分析超声特征结果显示,甲状腺未分化癌较甲状腺乳头状癌病灶大[(5.17±1.26)cm比(1.85±1.89)cm,P0.001]、纵横比1的比例高(100.0%比47.6%,P=0.03)、微钙化程度高(100.0%比52.4%,P=0.03)。两组在形态、边界、回声、均匀性、囊性变、血流状况、被膜受侵与否方面差异均无统计学意义(P均0.05)。结论老年女性甲状腺内最大径大于5 cm结节如具备常见的超声恶性征象,同时又存在纵横比小于1和微钙化,应高度怀疑未分化癌。
[Abstract]:Objective to study the difference of ultrasonographic features between undifferentiated thyroid carcinoma and papillary thyroid carcinoma. Methods from April 2001 to June 2014, the clinical and ultrasonic features of 7 patients with undifferentiated thyroid carcinoma, who had been admitted to Peking Union Hospital from April 2001 to June 2014, were retrospectively analyzed. Age matched 21 cases of thyroid papillary carcinoma confirmed by pathology as a control group, analysis of the two groups of ultrasound characteristics. Results the patients with undifferentiated thyroid carcinoma were mainly female. The average age of onset was 64.9 卤11.3 years. The results of ultrasonography showed that the focus of undifferentiated thyroid carcinoma was larger than that of papillary thyroid carcinoma [5.17 卤1.26)cm vs 1.85 卤1.89 cm ~ (-1) P0.001], the ratio of aspect to aspect was 100.0% higher than that of 47.6%, and the degree of microcalcification was 100.0% vs 52.4P0.03%. There were no significant differences in morphology, boundary, echo, homogeneity, cystic degeneration, blood flow status and invasion of the capsule between the two groups (P < 0.05). Conclusion if the largest diameter of thyroid gland is larger than 5 cm in elderly women, if there are common ultrasound malignant signs, the aspect ratio is less than 1 and microcalcification, undifferentiated carcinoma should be highly suspected.
【作者单位】：福建医科大学附属第一医院超声影像科;中国医学科学院北京协和医学院北京协和医院超声医学科;中国医学科学院北京协和医学院北京协和医院病理科;
【基金】：卫生部行业科研专项项目(201202012) 北京协和医院中青年科研基金(I104170)~~
【分类号】：R736.1;R445.1

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