直肠癌术前3.0T MR扩散加权成像b值的优化

发布时间：2018-05-28 03:45

本文选题：磁共振 + 扩散加权成像　；参考：《临床放射学杂志》2015年03期

【摘要】：目的比较不同扩散敏感系数(b值)对直肠癌病变的显示及对背景的抑制能力,探讨直肠癌术前3.0 T MR扩散加权成像(DWI)的合理b值。方法经病理证实直肠癌36例,术前行3.0 T MR DWI,b值取500、800、1000、1200、1500 s/mm2。分析各b值对肿瘤信号强度(ST),肿瘤信噪比(SNR),肿瘤与直肠系膜(CNRT/F)、肿瘤与盆壁肌肉(CNRT/M)等对比噪声比(CNR)的影响,以及各b值对肿瘤病变的显示及对背景的抑制能力。结果 ST、SNR、CNRT/F及CNRT/M分别在b值为1000 s/mm2~1200 s/mm2之间差异无明显统计学意义(P=0.22,P=0.119,P=0.102,P=0.161),而在b值1000或1200 s/mm2时差异有明显统计学意义(P0.05)。在各b值对肿瘤病变的显示及对背景的抑制能力判定中,主观评分在b值为1000 s/mm2~1200 s/mm2之间及1200 s/mm2~1500s/mm2之间差异无明显统计学意义(P=0.067、P=0.110),而在b值1000 s/mm2时差异有明显统计学意义(P0.05)。结论当b值取1000或1200 s/mm2时,既能获得良好的DWI图像,又能满足诊断需求,可作为直肠癌术前3.0 T MR扩散加权成像的合理b值。
[Abstract]:Objective to compare the ability of different diffusion-sensitive coefficients (DWI) to display and inhibit the background of rectal cancer, and to explore the reasonable b value of preoperative 3.0 T Mr diffusion weighted imaging (DWI) for rectal cancer. Methods 36 cases of rectal cancer proved by pathology were treated with 3. 0 T Mr DWIb value of 500 800 ~ 1 000 ~ 1 200 ~ 1 200 s / m ~ 2 路m ~ (-2) before operation. The effects of b values on the signal intensity, SNR, CNRT / FN, CNRTR / FN, CNRTR / M, and the ability of B values to display tumor lesions and inhibit the background were analyzed. Results there was no significant difference in s/mm2~1200 s/mm2 / F and CNRT/M between 1000 s/mm2~1200 s/mm2 and 0.22 s/mm2~1200 s/mm2, respectively, but there was a significant difference at b value of 1000 or 1200 s/mm2 (P 0.05%), while there was no significant difference between two groups (P = 0.22, P = 0.19, P = 0.102, P = 0.161, P = 1200). There was no significant difference between b value (1000 s/mm2~1200 s/mm2) and 1200 s/mm2~1500s/mm2 (P 0.067%, P 0.10 0 0 010), but there was significant difference between b value (1000 s/mm2) and 1200 s/mm2~1500s/mm2 (P 0.05). Conclusion when b value is 1000 or 1200 s/mm2, it can not only obtain good DWI images, but also meet the diagnostic needs. It can be used as a reasonable b value for 3.0T Mr diffusion-weighted imaging before operation for rectal cancer.
【作者单位】：湖北省肿瘤医院;
【分类号】：R445.2;R735.37

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