经直肠超声造影与彩色多普勒超声引导前列腺穿刺活检的对比研究

发布时间：2018-05-28 09:04

本文选题：经直肠超声造影 + 经直肠彩色多普勒超声　；参考：《新疆医科大学》2014年硕士论文

【摘要】：目的：探讨经直肠超声造影和彩色多普勒超声在经直肠灰阶超声引导前列腺穿刺活检应用价值对较。方法：选取2012年10月至2013年11月我院泌尿中心85例灰阶超声未检测出前列腺癌可疑病灶,实验室检查怀疑前列腺癌患者的临床资料,38例病例术前行经直肠超声造影,47例病例术前行经直肠彩色多普勒,对超声声像显像可疑病灶靶向行经直肠前列腺12点穿刺活检,分别比较两组组前列腺穿刺效能。结果：CEUS组靶向引导检测出前列腺癌阳性穿刺针数敏感性、阴性预测值较CDFI组高(P0.05)；特异性、阳性预测值两组差异无统计学意义(P0.05)。在PSA30ng/ml组中,两组间比较CEUS组敏感性CDFI组高(P0.05)；两组间特异性、阳性预测值和阴性预测值统计学无明显差异(P0.05)。在PSA30ng/ml组中两组间比较CEUS组敏感性、阴性预测值较CDFI组高(P0.05),特异性、阳性预测值差异无统计学意义(p0.05)o CEUS组穿刺阳性针Gleason评分9.03±0.751分较CDFI组8.72±0.690分高(P0.05),两组间术后并发症差异无统计学意义(P0.05)。结论：经直肠CEUS靶向引导前列腺穿刺活检较CDFI提高了穿刺点阳性针敏感性、阴性预测值,能避免不必要区域的穿刺；PSA30ng/ml病例中,经直肠TRUS靶向引导前列腺穿刺活检较经直肠CDFI提高阴性预测值,能避免不必要区域的穿刺；经直肠TRUS靶向引导前列腺穿刺活检阳性针较CDFI在Gleason4+3评分组中Gleason评分较高,能发现Gleason评分较高的前列腺癌。
[Abstract]:Objective: to evaluate the value of transrectal ultrasonography and color Doppler ultrasound in transrectal gray scale ultrasound guided prostate biopsy. Methods: from October 2012 to November 2013, 85 cases of suspected prostate cancer lesions were detected by gray scale ultrasonography in our urinary center. Clinical data of 38 patients suspected of Prostate Cancer before operation 47 patients with transrectal contrast-enhanced ultrasonography underwent transrectal color Doppler sonography and targeted transrectal biopsy of the prostate at 12:00. The efficacy of prostate puncture was compared between the two groups. Results the sensitivity of positive puncture needle number of prostate cancer was detected by targeting guidance in the group of: CEUS, and the negative predictive value was higher than that in the group of CDFI (P 0.05), but there was no significant difference between the two groups in specificity and positive predictive value (P 0.05). In PSA30ng/ml group, there was no significant difference in specificity, positive predictive value and negative predictive value between the two groups compared with CEUS group (P 0.05), the sensitivity of CEUS group was higher than that of CDFI group (P 0.05), and there was no significant difference between the two groups in terms of specificity, positive predictive value and negative predictive value. In PSA30ng/ml group, the sensitivity of CEUS group was higher than that of CDFI group, and the negative predictive value was higher than that of CDFI group. There was no significant difference in the positive predictive value between the two groups. The Gleason score of the puncture positive needle was 9.03 卤0.751in the CEUS group, which was higher than that in the CDFI group (8.72 卤0.690). There was no significant difference in postoperative complications between the two groups (P 0.05). Conclusion: compared with CDFI, transrectal CEUS targeted guided prostate biopsy can improve the sensitivity and negative predictive value of positive needle, and can avoid the unnecessary area of PSA30ng / ml cases. The negative predictive value of transrectal TRUS targeted guided prostate biopsy was higher than that of transrectal CDFI, and the puncture in unnecessary area could be avoided. The positive needle of transrectal TRUS targeted guided prostate biopsy was higher than that of CDFI in Gleason4 3 score group. Prostate cancer with high Gleason score can be found.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R445.1

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