二维超声联合四维超声诊断胎儿唇腭裂畸形的应用价值研究

发布时间：2018-06-06 00:34

本文选题：2D + 4D　；参考：《山西医科大学》2014年硕士论文

【摘要】：目的：探讨二维超声联合四维超声在诊断胎儿唇腭裂的应用价值，进一步提高胎儿唇腭裂畸形的超声检出率，为唇腭裂畸形的诊断、预后提供更多参考价值。方法：使用GEV olusonE8彩色多普勒超声诊断仪，2D探头频率2.0-5.0MHz，4D探头频率2.0-8.0MHz，支持4D模式。2012年1月至2014年3月在山西大医院妇产科彩超室行产前二维超声检查后疑似唇腭裂胎儿49例，联合四维超声进一步检查，根据二维和四维图像信息分别对唇腭裂的类型、部位、分度进行诊断记录，1-3月内随访患者。结果： 49例唇腭裂胎儿，单纯唇裂14例，2D超声确诊13例，检出率92.8%，4D超声确诊14例，检出率100%。唇腭裂35例，其中唇裂合并完全性腭裂33例，2D超声确诊23例，检出率69.6%，4D超声确诊25例，检出率75.7%；唇裂合并不完全性腭裂胎儿2例，2D及4D均未检出。37例单侧唇腭裂，2D误诊5例，4D误诊3例，12例非单侧唇腭裂，，2D误诊7例，4D误诊1例。结论： 1．2D联合4D对诊断唇腭裂畸形较2D超声具有更大优势。 2．2D超声对单纯唇裂和唇裂合并完全性腭裂的诊断相差无几，联合4D后对唇裂合并完全性腭裂的诊断准确度显著提高。 3．2D超声和4D超声对唇裂并不完全腭裂的诊断尚缺乏足够的证据，应用超声其他模式进行诊断可行进一步研究。
[Abstract]:Objective: to explore the value of two-dimensional ultrasound combined with four-dimensional ultrasound in the diagnosis of fetal cleft lip and palate, and to improve the detection rate of fetal cleft lip and palate. Methods: using GEV oluson E8 color Doppler ultrasound diagnostic instrument, the frequency of 2D probe was 2.0-5.0MHzn 4D, which supported 4D mode. From January 2012 to March 2014, 2-D prenatal ultrasound was performed in the color Doppler room of gynecology and obstetrics and gynecology and obstetrics of Shanxi Great Hospital. After ultrasonic examination, 49 cases of suspected cleft lip and palate fetus, According to the information of two-dimensional and four-dimensional images, the type, location and grading of cleft lip and palate were followed up within 1-3 months. Results: 49 cases of fetal cleft lip and palate, 14 cases of simple cleft lip and 14 cases of cleft lip were diagnosed by 2D ultrasound in 13 cases. The detection rate was 92. 8% and 14 cases were diagnosed by ultrasonography, and the detection rate was 100%. Among the 35 cases of cleft lip and palate, 23 cases were diagnosed by 2D ultrasonography in 33 cases of cleft lip and complete cleft palate, and 25 cases were diagnosed by 69.6 D ultrasound. The detection rate was 75.7%, 2 cases of fetal cleft lip with incomplete cleft palate were not detected in 2D and 4D. 37 cases of 2D misdiagnosis of unilateral cleft lip and palate in 5 cases were misdiagnosed in 3 cases and 12 cases of 2D misdiagnosis of non-unilateral cleft lip and palate in 7 cases of 4D misdiagnosed 1 case. Conclusion: 1. 2D combined with 4D pair misdiagnosis. 2. The diagnosis of cleft lip and cleft lip with complete cleft palate is similar to that of simple cleft lip and cleft lip with complete cleft palate. The diagnostic accuracy of cleft lip combined with complete cleft palate was significantly improved after combined with 4D. The diagnosis of cleft lip cleft palate with 3. 2D and 4 D ultrasound was not enough evidence. It was feasible to further study the diagnosis of cleft lip cleft palate by other modes of ultrasound.
【学位授予单位】：山西医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R445.1;R782.2

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