乳腺良恶性病灶超声造影定性及定量分析

发布时间：2018-06-07 22:35

本文选题：超声造影 + 乳腺肿块　；参考：《重庆医科大学》2014年硕士论文

【摘要】：目的：总结乳腺良恶性病灶超声造影特点，探讨超声造影技术在乳腺良恶性肿块中的鉴别诊断价值。方法：对2013年3月~2013年11月我院107例乳腺肿块患者进行超声造影检查，对肿块的增强方式及时间-强度曲线进行分析，总结乳腺良恶性肿块的超声造影特点。结果：病理诊断93个病灶，其中恶性52个，良性41个。52个恶性病灶中，47个表现为不均匀增强(90.38％)，39个表现为高增强(75.0%),增强后边界均显示不清（100％），其中32个病灶见造影剂滞留（61.54％），23个病灶见穿支血管显影（44.23％）。41个良性病灶中，32个病灶表现为均匀增强(78.05%)，增强程度以等增强和低增强为主，亦可有高增强、无增强。28个病灶增强后边界清楚（68.30%），，35个病灶无造影剂滞留（85.37%），38个病灶无穿支血管（92.68%）。时间-强度曲线中恶性病灶呈现快速上升后缓慢阶梯状下降，良性病灶呈现快速上升后迅速下降，恶性病灶时间-强度曲线开始增强时间（Wash-in-time）较良性早，峰值强度（Peak intensity）较良性病灶大，恶性组开始增强时间(10.56±3.78s)、峰值强度（36.20±15.18dB）与良性组比较差异具有统计学意义（P＜0.05）。恶性组与良性组达峰时间（Time to peak）、峰值强度减半时间（Half of Peakintensity）分别比较，两者间差异无统计学意义（P＞0.05）。结论：通过超声造影发现乳腺良恶性病灶增强模式具有一定特征性表现，结合造影时间-强度曲线分析有助于对乳腺良恶性肿瘤的鉴别诊断。
[Abstract]:Objective: to summarize the contrast-enhanced features of benign and malignant breast lesions and to evaluate the value of contrast-enhanced ultrasonography in differential diagnosis of benign and malignant breast masses. Methods: from March 2013 to November 2013, 107 patients with breast masses in our hospital were examined by contrast-enhanced ultrasonography. The enhancement mode and time-intensity curve of breast masses were analyzed, and the contrast-enhanced features of benign and malignant breast masses were summarized. Results: 93 lesions were diagnosed by pathology, of which 52 were malignant. Of the 41 benign and 52 malignant lesions, 47 showed heterogeneous enhancement (90.38%), 39 showed high enhancement (75.0%), and the boundary of enhancement showed 100% indistinct. Of these, 32 lesions showed contrast agent retention (61.54), 23 lesions showed perforator vessel imaging and 41 benign lesions. Among them, 32 lesions showed homogeneous enhancement (78.05), and the degree of enhancement was mainly equal enhancement and low enhancement. There were also high enhancement and no enhancement. After enhancement, 28 lesions had clear boundary 68.30, 35 lesions had no contrast agent, and 38 lesions had no perforating vessels 92.68%. In the time-intensity curve, the malignant lesions showed a rapid rise and then a slow step down, and the benign lesions showed a rapid rise and then a rapid decline, and the time of enhancement of the malignant lesions began to be Wash-in-time earlier than that of the benign lesions. The peak intensity of peak intensity was larger than that of benign lesions. The time of enhancement was 10.56 卤3.78 s-1, and the peak intensity was 36.20 卤15.18 dB. There was significant difference between malignant group and benign group (P < 0.05). There was no significant difference between malignant group and benign group (P > 0.05). Conclusion: contrast-enhanced mode of benign and malignant breast lesions is characteristic by contrast-enhanced ultrasonography. The analysis of time-intensity curve is helpful to the differential diagnosis of breast benign and malignant tumors.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R445.1

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