乳腺导管原位癌及浸润癌超声表现与病理相关性新探

发布时间：2018-06-10 06:41

本文选题：超声检查 + 导管原位癌　；参考：《中国超声医学杂志》2017年06期

【摘要】：目的比较乳腺导管原位癌(DCIS)与浸润性导管癌(IDC)超声表现的差异,探讨超声对DCIS的诊断价值。方法回顾性总结145个穿刺病理为DCIS的病例,其中88个得到术后病理证实,57个为IDC伴DCIS;抽取同一时间段300个IDC病例,比较三类病变声像图差异,分析DCIS病理分级与超声表现的关系。结果三组平均最大径、后方回声、伴微小钙化及乳导管扩张的比例有显著差异,IDC与DCIS组差异较大,而穿刺病理低估组的超声表现介于二者之间。DCIS组表现为结构紊乱区26个(29.5%)、占位性病变62个(70.5%)。高级别DCIS平均最大径及伴微小钙化的比例更高。结论 DCIS由低到高级别、由原位癌进展为浸润癌在超声表现中是递进的。近1/3的DCIS没有占位效应,临床工作中应提高警惕。
[Abstract]:Objective to compare the difference between DCIS and IDC in breast ductal carcinoma in situ and to evaluate the value of ultrasonography in diagnosis of DCIS. Methods one hundred and forty-five cases with DCIS were retrospectively summarized, of which 88 cases were confirmed by postoperative pathology, 57 cases were IDC with DCIS, 300 cases of IDC were selected in the same time period, and the sonographic differences of three types of lesions were compared. To analyze the relationship between DCIS pathological grade and ultrasonic findings. Results there were significant differences in the average maximum diameter, posterior echo, microcalcification and mammary duct dilatation between the three groups. The difference between IDC group and DCIS group was greater than that in DCIS group. The ultrasound findings of the undervalued puncture pathology group were between the two groups. The DCIS group showed 26 lesions in the structural disorder area of 29.5% and 62 lesions in the space occupying area of 70.5%. The average maximum diameter of high grade DCIS and the proportion of patients with microcalcification were higher. Conclusion DCIS is progressive from low to high grade, from carcinoma in situ to invasive carcinoma. Nearly a third of DCIS has no space occupying effect and should be vigilant in clinical work.
【作者单位】：北京大学肿瘤医院暨北京市肿瘤防治研究所乳腺中心恶性肿瘤发病机制及转化研究教育部重点实验室;
【分类号】：R445.1;R737.9

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