不同年龄段高血压左室舒张功能变化对颈动脉血流动力学影响的超声研究

发布时间：2018-06-18 06:07

本文选题：左室舒张功能 + 颈动脉血流参数　；参考：《新疆医科大学》2014年硕士论文

【摘要】：目的：采用脉冲多普勒超声技术测量二尖瓣舒张期血流频谱及颈部动脉血流频谱,探讨不同年龄组高血压患者左室舒张功能与颈动脉血流动力学特征之间的关系。方法：选择高血压患者608例,测量二尖瓣瓣口舒张期血流E峰及A峰,根据E峰及A峰的比值(E/A),按照E/A1和E/A1分成两组,两组内按年龄分为青年组、中年组和老年组,使用高频探头测量颈总动脉、颈内动脉及椎动脉的收缩期峰速度(PSV)、舒张末期流速(EDV)、阻力指数(P1)、搏动指数(RI)。各年龄组内又使用spss17.0对组内,组间进行统计学分析。两组间颈动脉血流动力学参数根据分组采用独立t检验；各组二尖瓣舒张期血流指标与颈动脉血流动力学参数采用相关性分析；多组间的血流动力学指标用单因素方差分析,方差不齐者用秩和检验。结果：三个年龄组的高血压患者组间比较：E/A1时,颈总动脉血流参数PSV、PI、RI随年龄的增长而降低。E/A1时,颈总动脉PSV、EDV和椎动脉PSV均随年龄的增长而降低,颈总动脉和颈内动脉的PI、RI随年龄的增长而增高。E/A1组与E/A1组相比,老年组内颈总动脉、颈内动脉及椎动脉血流参数EDV下降,PI、RI升高。结论：左室舒张功能受损时,颈部血管随增龄血管顺应性减退,血流阻力增加。
[Abstract]:Objective: to investigate the relationship between left ventricular diastolic function and carotid artery hemodynamics in patients with hypertension of different ages by measuring mitral diastolic flow spectrum and carotid artery flow spectrum by pulsed Doppler ultrasound. Methods: the diastolic E and A peak of mitral valve orifice were measured in 608 patients with hypertension. According to the ratio of E / A peak and E / A peak, the patients were divided into two groups according to the ratio of E / A 1 and E / A 1. The two groups were divided into three groups according to their age: young group, middle age group and elderly group. The systolic peak velocities of common carotid artery, internal carotid artery and vertebral artery were measured by high frequency probe. Spss17.0 was also used in all age groups for statistical analysis. The carotid artery hemodynamic parameters of each group were analyzed by independent t test according to the grouping; the correlation analysis between mitral diastolic blood flow index and carotid artery hemodynamic parameter was used in each group; the hemodynamic parameters of multiple groups were analyzed by single factor variance analysis. Those with uneven variances were tested by rank sum test. Results: compared with the age group, the common carotid artery blood flow parameter PSV / PII RI decreased with the age. The common carotid artery PSV EDV and vertebral artery PSV decreased with the age of the patients with hypertension, and with the increase of age, the common carotid artery PSV EDV and the vertebral artery PSV decreased with the increase of age, and the blood flow parameters of the common carotid artery (PSV) and vertebral artery decreased with the increase of age. The PIRI of the common carotid artery and the internal carotid artery increased with age. Compared with the E / A1 group, the blood flow parameters of the common carotid artery, the internal carotid artery and the vertebral artery in the elderly group were decreased, and the blood flow parameters of the common carotid artery, the internal carotid artery and the vertebral artery in the elderly group were increased. Conclusion: when left ventricular diastolic function is impaired, the blood flow resistance increases with the decrease of vascular compliance.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R445.1

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