妊娠相关蛋白A水平与冠状动脉斑块稳定性关系的虚拟组织学血管内超声研究

发布时间：2018-06-20 05:41

  本文选题：冠状动脉疾病 + 妊娠相关蛋白A　； 参考：《中国超声医学杂志》2015年03期

【摘要】：目的探讨血清妊娠相关蛋白A(PAPP-A)水平与冠状动脉斑块稳定性的关系。方法对96例不稳定性心绞痛(UA)患者行虚拟组织学血管内超声(VH-IVUS)检查,采用酶联免疫吸附法测定血清PAPP-A水平。结果根据VH-IVUS结果,将患者分为薄帽纤维粥样硬化(TCFA)组和非TCFA组,TCFA组患者PAPP-A水平高于非TCFA组患者。PAPP-A水平≥11.0mIU/L(OR=4.564,P=0.002)和坏死核心体积百分比(OR=1.144,P=0.029)是TCFA的独立预测因素。结论血清PAPP-A水平与TCFA有相关。PAPP-A水平≥11.0mIU/L和坏死核心体积百分比是TCFA的独立预测因素。
[Abstract]:Objective to investigate the relationship between serum pregnancy-associated protein (PAPP-A) and coronary plaque stability. Methods 96 patients with unstable angina pectoris (UAA) were examined by virtual histologic intravascular ultrasound (VH-IVUS) and the serum PAPP-A levels were measured by Elisa (enzyme linked immunosorbent assay). Results according to the results of VH-IVUS, the PAPP-A level of TCFA group was higher than that of non-TCFA group. The PAPP-A level of TCFA group was higher than that of non-TCFA group (鈮，

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