乳腺癌新辅助化疗前后超声造影表现

发布时间：2018-06-28 22:24

本文选题：乳腺肿瘤 + 超声检查　；参考：《中国介入影像与治疗学》2015年01期

【摘要】：目的探讨乳腺癌新辅助化疗前后的超声造影表现。方法将接受乳腺癌新辅助化疗(NAC)的31例患者作为研究对象,以术前的穿刺病理和术后的手术病理为参照标准,比较化疗前后肿瘤的超声造影增强模式,并应用时间-强度曲线分析软件对参数进行分析。结果乳腺癌NAC前后,肿瘤的CEUS类型以不均匀增强为主[化疗前(18/31,58.06%),化疗后(21/31,67.74%)],化疗后无增强的肿瘤明显增多[(化疗前0,化疗后(5/31,16.13%)]。造影参数分析:化疗后的上升时间增加,峰值强度及曲线下面积降低,差异均有统计学意义(P均0.05)。结论乳腺癌NAC前后,肿瘤的CEUS增强类型以不均匀增强为主,化疗后无增强的比例明显增高。化疗前后肿瘤CEUS的时间-强度曲线指标中,上升时间、峰值强度和曲线下面积是有价值的指标。
[Abstract]:Objective to investigate the contrast-enhanced findings of breast cancer before and after neoadjuvant chemotherapy. Methods Thirty-one patients with breast cancer received neoadjuvant chemotherapy (NAC) were studied. The contrast-enhanced mode of contrast-enhanced ultrasound was compared before and after chemotherapy. The time-strength curve analysis software is used to analyze the parameters. Results before and after NAC, the type of CEUs in breast cancer was mainly enhanced inhomogeneously [before chemotherapy (18 / 31) (58.06%), after chemotherapy (21 / 31 + 67.74%)], the number of tumors without enhancement after chemotherapy was significantly increased [(0% before chemotherapy, 16.13% after chemotherapy)]. Analysis of contrast parameters: after chemotherapy, the rising time increased, the peak intensity and the area under the curve decreased, the difference was statistically significant (P 0.05). Conclusion before and after NAC, the enhancement types of CEUs in breast cancer are mainly uneven enhancement, but the proportion of non-enhancement after chemotherapy is significantly increased. In the time intensity curve of CEUs before and after chemotherapy, the rising time, the peak intensity and the area under the curve are valuable indexes.
【作者单位】：四川大学华西医院超声科;
【分类号】：R445.1;R737.9

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