超声心动图对胎儿假性左心发育不良的研究

发布时间：2018-07-06 21:27

本文选题：左心发育不良综合征 + 假性左心发育不良　；参考：《福建医科大学》2014年硕士论文

【摘要】：【目的】探讨应用胎儿超声心动图对假性左心发育不良的诊断价值。【材料与方法】将胎儿超声心动图检出的部分性肺静脉异位引流15例，，主动脉缩窄20例，房间隔膨出瘤30例与正常组50例以及左心发育不良综合征14例的胎儿的心脏数据如左房、右房、左室、右室、左心房/右心房比值、左心室/右心室比值、主动脉、肺动脉进行比较分析，研究除左心发育不良综合征之外的心血管结构异常与形态异常对左心发育的影响。【结果】 1、正常组：左房、右房、左室、右室、主动脉、肺动脉内径分别为（11.742±1.508）cm、（13.330±1.718）cm、（11.392±1.668）cm、（12.354±1.581）cm、（6.262±0.854）cm、（7.612±1.040）cm，、左房/右房比值为（0.883±0.072），左室/右室比值为（0.920±0.044）。 2、异常组：部分性肺静脉异位引流组、主动脉缩窄组、房间隔膨胀瘤组的的左房、左室、左房/右房比值、左室/右室比值比正常组小（P0.05P=0.000），右房、右室值比正常组大（P0.05，P=0.000）；部分性肺静脉异位引流组、主动脉缩窄组及房间隔膨胀瘤组主动脉比正常组小（P0.05P=0.000）；主动脉缩窄组的肺动脉比正常组大（P0.05），房间隔膨胀瘤组的肺动脉比正常组小（P0.05P=0.000）。部分性肺静脉异位引流组、主动脉缩窄组、房间隔膨胀瘤组的左房、右房、左房/右房、左室、右室、左室/右室值都比左心发育不良综合征组大（P0.05P=0.000）；肺静脉异位引流组的肺动脉比左心发育不良综合征组比小（P0.05P=0.000），主动脉缩窄组、房间隔膨胀瘤组的主动脉、肺动脉都比左心发育不良综合征组大（P0.05P=0.000）。【结论】胎儿超声心动图是研究左心发育不良的的重要且方便的方法。部分性肺静脉异位引流、主动脉缩窄、房间隔膨出瘤可引起左心发育相对差，但与真正的左心发育不良综合征相比具有显著差异。
[Abstract]:[Objective]
Objective to investigate the diagnostic value of fetal echocardiography in pseudohypoplasia of left heart.
[materials and methods]
15 cases of partial pulmonary venous drainage detected by fetal echocardiography, 20 cases of coarctation of aorta, 30 cases of atrial septal aneurysm, 50 cases of normal group and 14 cases of left heart dysplasia syndrome, such as left atrium, right chamber, left ventricle, right ventricle, right atrium ratio, left ventricular / right ventricular ratio, aorta and pulmonary artery. A comparative analysis was conducted to study the effects of cardiovascular structural abnormalities and abnormal morphology on left ventricular development in addition to left ventricular hypoplasia syndrome.
[results]
1, in the normal group, the left atrium, right atrium, left ventricle, right ventricle, aorta and pulmonary artery were (11.742 + 1.508) cm, (13.330 + 1.718) cm, (11.392 + 1.668) cm, (12.354 + 1.581) cm, (6.262 + 0.854) cm and (7.612 + 1.040) cm, and the ratio of left atrial / right chamber (left ventricular / right chamber) was (left ventricular / right ventricular ratio).
2, abnormal group: the partial pulmonary venous ectopic drainage group, the coarctation group of the aorta, the left atrium, the left atrium / right atrium ratio, the left ventricular / right ventricular ratio smaller than the normal group (P0.05P=0.000), the right chamber and right ventricular value larger than the normal group (P0.05, P=0.000); the partial pulmonary venous ectopic drainage group, the coarctation group of the aorta and the atrial septum tumor. The aorta of the group was smaller than the normal group (P0.05P=0.000); the pulmonary artery in the coarctation group of the aorta was larger than the normal group (P0.05), and the pulmonary artery of the atrial septal expansive tumor group was smaller than the normal group (P0.05P=0.000). The partial pulmonary venous ectopic drainage group, the coarctation group of the aorta, the left atrium, the left atrium / right chamber, the left ventricle, the left ventricle, the left ventricle / right ventricular value were all in the group of atrial septum expansive tumor. Compared to the left heart dysplasia syndrome group (P0.05P=0.000), the pulmonary artery in the pulmonary venous drainage group was smaller than the left heart dysplasia group (P0.05P=0.000), the aorta coarctation group, the atrial septum swelling group of the aorta and the pulmonary artery were larger than the left heart dysplasia syndrome group (P0.05P=0.000). [conclusion] fetal echocardiography is a research study. An important and convenient approach to left heart dysplasia. Partial anomalous pulmonary venous drainage, coarctation of the aorta, and atrial septal aneurysm may cause a relatively poor left heart development, but are significantly different from the real left heart dysplasia syndrome.
【学位授予单位】：福建医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R445.1

【参考文献】