超声心动图预测慢性充血性心力衰竭患者心脏再同步化治疗急性反应
发布时间：2018-07-13 11:30
【摘要】：目的探讨超声心动图预测慢性充血性心力衰竭(CHF)患者心脏再同步化治疗(CRT)急性反应的价值。方法选取接受CRT的CHF患者33例,分别在CRT开启(ON)和关闭(OFF)状态下进行超声心动图检查,测量左心房最大前后径(LAD)、左心室舒张末内径(LVEDD)、左心室射血分数(LVEF)、房室同步性(A-V-D)、心室间同步性(V-V-D)。采用组织多普勒技术(TDI)测量左心室收缩(Vs-T-SD)和舒张同步性(Ve-T-SD);实时三维超声心动图(RT-3DE)检测左心室收缩同步性(T16-SD%)。将CRT-ON时,LVEF增加≥5%设为有反应(CRT-R)组,5%为无反应(CRT-NR)组。对以上数据进行统计学分析。结果25例患者(25/33,75.76%)为CRT-R组,8例(8/33,24.24%)为CRT-NR组。CRT-R组,CRT-ON时QRSd、LVEDD、LVESD、LAD、LVEDV、LVESV、V-V-D和T16-SD%较CRT-OFF时减小,LVSV和LVEF增加(P均0.05);CRT-NR组,CRT-ON时LVEDD、LVESD和LAD较CRT-OFF时减小,LVEF增加(P均0.05)。术前CRT-R组LAD和LVEDD小于CRT-NR组,而左束支传导阻滞和非缺血性心肌病患者的比例、V-V-D大于CRT-NR组(P均0.05)。V-V-D为44ms时,曲线下面积为0.747,预测CRT急性反应有效的敏感度及特异度分别为60.0%和87.5%(P0.05)。结论 LAD和LVEDD较小、室间同步性较差且合并左束支传导阻滞的非缺血性心肌病的CHF患者更可能CRT急性反应有效,V-V-D可准确预测CRT急性反应。
[Abstract]:Objective to evaluate the value of echocardiography in predicting acute cardiac resynchronization therapy (CRT) in patients with chronic congestive heart failure (CHF). Methods Thirty-three patients with CHF receiving CRT were examined by echocardiography under the condition of CRT open (on) and off (off) respectively. Left atrial maximum anteroposterior diameter (lad), left ventricular end-diastolic diameter (LVEDD), left ventricular ejection fraction (LVEF), atrioventricular synchrony (A-V-D) and interventricular synchrony (V-V-D) were measured. Left ventricular contraction (Vs-T-SD) and diastolic synchrony (Ve-T-SD) were measured by tissue Doppler technique (TDI), and left ventricular systolic synchrony (T16-SD%) was measured by real-time three-dimensional echocardiography (RT-3DE). The increase of LVEF 鈮，
本文编号：2119208
[Abstract]:Objective to evaluate the value of echocardiography in predicting acute cardiac resynchronization therapy (CRT) in patients with chronic congestive heart failure (CHF). Methods Thirty-three patients with CHF receiving CRT were examined by echocardiography under the condition of CRT open (on) and off (off) respectively. Left atrial maximum anteroposterior diameter (lad), left ventricular end-diastolic diameter (LVEDD), left ventricular ejection fraction (LVEF), atrioventricular synchrony (A-V-D) and interventricular synchrony (V-V-D) were measured. Left ventricular contraction (Vs-T-SD) and diastolic synchrony (Ve-T-SD) were measured by tissue Doppler technique (TDI), and left ventricular systolic synchrony (T16-SD%) was measured by real-time three-dimensional echocardiography (RT-3DE). The increase of LVEF 鈮，
本文编号：2119208
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