超声动脉分析技术评价妊娠期高血压患者的颈动脉径向应变和应变率
发布时间：2018-07-15 15:44
【摘要】：目的应用动脉分析技术分析妊娠期高血压(PIH)患者的颈动脉血管弹性及径向应变、应变率,并与妊娠期无高血压的正常孕妇进行对比研究。方法选取于我院就诊的PIH患者28例作为病例组(PIH组),同期选取正常妊娠女性30例作为对照组(正常妊娠组)。应用动脉分析技术通过追踪颈动脉血管壁的运动,自动获取颈动脉弹性参数及径向应变、应变率等数据,并进行统计学分析。结果 PIH组的颈动脉血管僵硬度β、脉搏波传导速度较正常妊娠组明显增高,而血管顺应性则较正常妊娠组明显减低,差异均有统计学意义(P0.05),反射波增强指数的差异无统计学意义。PIH组整体径向应变、整体径向应变率较正常妊娠组相比明显减低,差异有统计学意义(P0.05),其中径向应变与脉搏波传导速度呈显著负相关。结论血管整体径向应变和应变率可以作为反映PIH患者血管弹性变化的有效指标,且径向应变比径向应变率更加敏感。动脉分析技术通过以上反映颈动脉功能的敏感指标,可以及早发现PIH患者血管弹性的减低,在血管形态学未发生改变之前为临床预防和治疗提供依据。
[Abstract]:Objective to analyze the carotid artery elasticity, radial strain and strain rate in patients with hypertension complicating pregnancy (PIH) by arterial analysis, and to compare the results with those of normal pregnant women without hypertension during pregnancy. Methods 28 PIH patients in our hospital were selected as the case group (PIH group) and 30 normal pregnant women as the control group (normal pregnancy group). By tracking the movement of carotid artery wall, the data of carotid elastic parameters, radial strain and strain rate were obtained automatically by means of arterial analysis, and statistical analysis was carried out. Results the carotid artery stiffness 尾 and pulse wave velocity in PIH group were significantly higher than those in normal pregnancy group, while vascular compliance was significantly lower in PIH group than in normal pregnancy group. All the differences were statistically significant (P0.05). There was no significant difference in reflection wave enhancement index. The global radial strain rate of PIH group was significantly lower than that of normal pregnancy group. The difference was statistically significant (P0.05), in which radial strain and pulse wave velocity were negatively correlated. Conclusion Radial strain and strain rate can be used as an effective index to reflect vascular elasticity in PIH patients, and radial strain is more sensitive than radial strain rate. Through the above sensitive indexes which reflect carotid artery function, the reduction of vascular elasticity in PIH patients can be detected as early as possible, which can provide evidence for clinical prevention and treatment before the change of vascular morphology.
【作者单位】： 中国医科大学附属盛京医院超声科;
【基金】：国家自然科学基金(81571686)
【分类号】：R445.1;R714.246
本文编号：2124575
[Abstract]:Objective to analyze the carotid artery elasticity, radial strain and strain rate in patients with hypertension complicating pregnancy (PIH) by arterial analysis, and to compare the results with those of normal pregnant women without hypertension during pregnancy. Methods 28 PIH patients in our hospital were selected as the case group (PIH group) and 30 normal pregnant women as the control group (normal pregnancy group). By tracking the movement of carotid artery wall, the data of carotid elastic parameters, radial strain and strain rate were obtained automatically by means of arterial analysis, and statistical analysis was carried out. Results the carotid artery stiffness 尾 and pulse wave velocity in PIH group were significantly higher than those in normal pregnancy group, while vascular compliance was significantly lower in PIH group than in normal pregnancy group. All the differences were statistically significant (P0.05). There was no significant difference in reflection wave enhancement index. The global radial strain rate of PIH group was significantly lower than that of normal pregnancy group. The difference was statistically significant (P0.05), in which radial strain and pulse wave velocity were negatively correlated. Conclusion Radial strain and strain rate can be used as an effective index to reflect vascular elasticity in PIH patients, and radial strain is more sensitive than radial strain rate. Through the above sensitive indexes which reflect carotid artery function, the reduction of vascular elasticity in PIH patients can be detected as early as possible, which can provide evidence for clinical prevention and treatment before the change of vascular morphology.
【作者单位】： 中国医科大学附属盛京医院超声科;
【基金】：国家自然科学基金(81571686)
【分类号】：R445.1;R714.246
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1 郭薇;欧宓;王春;;超声的二维径向应变显像对心肌缺血的研究[J];中国超声医学杂志;2007年11期
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